Repeatability and agreement of two ocular biometers with single and dual Scheimpflug cameras in keratoconus eyes.

IF 2.4 3区医学 Q2 OPHTHALMOLOGY

Graefe’s Archive for Clinical and Experimental Ophthalmology Pub Date : 2024-11-01 Epub Date: 2024-07-24 DOI:10.1007/s00417-024-06511-z

Christoph Lwowski, Daniel Krüger, Thomas Kohnen

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Abstract

Background: To evaluate the repeatability and agreement of two different ocular biometers and Scheimpflug devices in keratoconus eyes.

Methods: This prospective, comparative trial took place at the University hospital, Goethe University, Frankfurt am Main, Germany. We included eyes with keratoconus, one eye per patient, randomly selected. Measurements were taken with Galilei G6 (Ziemer, Switzerland) and Pentacam AXL (Oculus, Germany), three consecutive measurements each. Repeatability and agreement were evaluated for simulated keratometry (simK), astigmatism (simA), maximum keratometry (KMax) and its axis, total keratometry (TCP), axial length (AL), anterior chamber depth (ACD), and thinnest pachymetry (TCT).

Results: Both devices showed an excellent repeatability with intra class correlation (ICC) of > 0.97 for all parameters. The 95% limits of repeatability (LoR95%) and agreement (LoA95%) were narrow for all parameters. The Galilei G6 had a narrower LoAR95% for TCT (2.1 μm vs. 4.6 μm), but a wider LoR95% for KMax (0.52D vs. 1.18D). No relevant difference was found for the other parameters. Agreement between the devices was good to moderate, especially for simK and TCP.

Conclusions: Both devices show excellent repeatability with narrow LoR95% and high ICC for all parameters. The only relevant difference was found for KMax and TCT in favor of Pentacam AXL and Galilei G6, respectively. Agreement was good to moderate, and most parameters should not be considered interchangeable.

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在角膜炎患者眼中使用单双 Scheimpflug 相机的两种眼球生物测量仪的重复性和一致性。

背景：评估两种不同的眼球生物测量仪和 Scheimpflug 设备在角膜炎患者眼中的重复性和一致性：评估两种不同的眼球生物测量仪和 Scheimpflug 设备在角膜炎患者眼中的重复性和一致性：这项前瞻性比较试验在德国美因河畔法兰克福歌德大学附属医院进行。我们随机抽取了每位患者的一只角膜炎眼。使用 Galilei G6（瑞士 Ziemer 公司）和 Pentacam AXL（德国 Oculus 公司）进行测量，每次连续测量三次。对模拟角膜度量（simK）、散光（simA）、最大角膜度量（KMax）及其轴、总角膜度量（TCP）、轴向长度（AL）、前房深度（ACD）和最薄厚度（TCT）的重复性和一致性进行了评估：两种设备都显示出极佳的重复性，所有参数的类内相关性（ICC）均大于 0.97。所有参数的重复性 95% 限值（LoR95%）和一致性 95% 限值（LoA95%）都很窄。Galilei G6 的 TCT LoAR95% 较窄（2.1 μm 对 4.6 μm），但 KMax LoR95% 较宽（0.52D 对 1.18D）。其他参数没有发现相关差异。设备之间的一致性良好至中等，尤其是 simK 和 TCP：结论：两种仪器都显示出极佳的重复性，所有参数的 LoR95% 都很窄，ICC 都很高。唯一的相关差异是 KMax 和 TCT，分别有利于 Pentacam AXL 和 Galilei G6。一致性良好至中等，大多数参数不应被视为可以互换。

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来源期刊

Graefe’s Archive for Clinical and Experimental Ophthalmology 医学-眼科学

CiteScore

5.40

自引率

7.40%

发文量

398

审稿时长

3 months

期刊介绍： Graefe''s Archive for Clinical and Experimental Ophthalmology is a distinguished international journal that presents original clinical reports and clini-cally relevant experimental studies. Founded in 1854 by Albrecht von Graefe to serve as a source of useful clinical information and a stimulus for discussion, the journal has published articles by leading ophthalmologists and vision research scientists for more than a century. With peer review by an international Editorial Board and prompt English-language publication, Graefe''s Archive provides rapid dissemination of clinical and clinically related experimental information.