Local Therapy for Metastatic Colorectal Cancer: A Case-Based Review.

IF 2.6 4区 医学 Q3 ONCOLOGY
Michael P Dykstra, Smith Apisarnthanarax, George Poultsides, Katelyn M Atkins, David Binder, Jeffrey Olsen, Dayssy Alexandra Diaz, Daniel T Chang
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引用次数: 0

Abstract

Abstract: The oligometastatic disease state, defined as a cancer with 5 or fewer sites of metastasis, is a therapeutic opportunity to improve oncologic outcomes. Colorectal cancer (CRC) was among the first for which oligometastatic treatment was used in routine clinical practice, and recent studies have shown potential for improved overall survival with metastasis-directed therapies. As CRC is the third most common cause of cancer death in men and women, improving oncologic outcomes in this population is of paramount importance. The relatively recent identification of this treatment paradigm and paucity of high-quality data have led to heterogeneity in clinical practice. This review will explore perspectives of a panel of surgical and radiation oncologists for complex or controversial cases of metastatic CRC.

转移性结直肠癌的局部治疗:基于病例的综述。
摘要:少转移疾病状态是指癌症的转移部位少于或等于5个,它是改善肿瘤治疗效果的一个治疗机会。结直肠癌(CRC)是常规临床实践中最早使用少转移治疗的癌症之一,最近的研究表明,转移导向疗法有可能提高总生存率。由于 CRC 是导致男性和女性癌症死亡的第三大常见原因,因此改善这一人群的肿瘤治疗效果至关重要。由于这种治疗模式的确定相对较晚,且高质量的数据较少,因此在临床实践中出现了异质性。本综述将探讨外科和放射肿瘤专家小组对复杂或有争议的转移性 CRC 病例的看法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Cancer journal
Cancer journal 医学-肿瘤学
CiteScore
3.90
自引率
0.00%
发文量
102
审稿时长
7.5 months
期刊介绍: The Cancer Journal: The Journal of Principles & Practice of Oncology provides an integrated view of modern oncology across all disciplines. The Journal publishes original research and reviews, and keeps readers current on content published in the book Cancer: Principles & Practice of Oncology.
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