Subtotal resection of vestibular schwannoma with subsequent Gamma Knife irradiation - tumor growth control, facial and cochlear nerve outcome - preliminary results.

IF 1 Q3 OTORHINOLARYNGOLOGY
Grzegorz Turek, Adrian Drożdż, Sebastian Dzierzęcki, Karolina Dżaman, Mariusz Gruda, Justyna Zielińska-Turek, Jan Gajewski, Dominika Bodzak, Mirosław Ząbek
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引用次数: 0

Abstract

<b>Introduction:</b> The choice of treatment of vestibular schwannoma (VS) depends on several factors, including the tumor size, the patient's age and overall health, and the presence and severity of symptoms.<b>Aim:</b> The aim of the study was to assess the effectiveness of intentional subtotal resection (STR) of tumor followed by Gamma Knife surgery (GKS) in patients with larger VS (Koos 3 and 4).<b>Materials and methods:</b> The retrospective analysis was performed on 18 patients. Data of VS volumes measured in MRI, the facial nerve function assessed in the House-Brackmann scoring system (HB), and the results of audiological examination expressed on the Gardner-Robertson scale (GR) were collected preoperatively, postoperatively, and post-GKS.<b>Results:</b> Preoperatively, the main symptom was hearing loss observed in 13 out of 18 patients. The facial nerve function was assessed as HB 1 in 16, whereas HB 2 in 2 patients. The mean volume of the tumor in the initial MRI amounted to 16.81 cm<sup>3</sup> . Postoperatively, the facial nerve was assessed as HB 1 or 2 in 16, whereas HB 3 in 2 patients. Serviceable hearing was presented by only 4 persons. The Mean diameter of the tumor after subtotal surgery amounted to 3.16 cm<sup>3</sup> , 1.83 cm<sup>3</sup> after GKS, and 1.58 cm<sup>3</sup> at the last follow-up. The facial nerve function and hearing level remained the same as before GKS in all patients.<b>Conclusions:</b> STR followed by GKS can be a safe and effective method of treatment of large VS concerning the functional outcome of the facial nerve and the tumor volume growth control.

前庭分裂瘤次全切除术后伽玛刀照射--肿瘤生长控制、面部和耳蜗神经疗效--初步结果。
<b>引言:</b>前庭分裂瘤(VS)治疗方法的选择取决于多种因素,包括肿瘤大小、患者年龄和整体健康状况以及症状的存在和严重程度。<b>目的:</b>该研究旨在评估对较大型 VS(Koos 3 和 4)患者进行肿瘤意向性次全切除术(STR)后再进行伽玛刀手术(GKS)的有效性。收集了核磁共振成像测量的 VS 体积数据、House-Brackmann 评分系统(HB)评估的面神经功能数据以及以 Gardner-Robertson 量表(GR)表示的听力检查结果。16 名患者的面神经功能评估为 HB 1,2 名患者为 HB 2。初次核磁共振成像中肿瘤的平均体积为 16.81 厘米<sup>3</sup>。术后,16 名患者的面神经被评估为 HB 1 或 2,而 2 名患者的面神经被评估为 HB 3。只有 4 人听力正常。次全切手术后肿瘤的平均直径为 3.16 cm<sup>3</sup>,GKS 手术后为 1.83 cm<sup>3</sup>,最后一次随访时为 1.58 cm<sup>3</sup>。<b>结论:</b>在面神经功能结果和肿瘤体积生长控制方面,STR 后 GKS 是一种安全有效的大型 VS 治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Polish Journal of Otolaryngology
Polish Journal of Otolaryngology OTORHINOLARYNGOLOGY-
CiteScore
1.30
自引率
16.70%
发文量
15
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