Detection of Anti-Strongyloides Antibodies in the Serum of Liver Transplant Recipients: Need of Screening for This Neglected Helminthiasis.

IF 1.4 4区医学 Q4 IMMUNOLOGY

Parasite Immunology Pub Date : 2024-07-01 DOI:10.1111/pim.13059

Marcelo Andreetta Corral, Dirce Mary Correia Lima Meisel, Michele Soares Gomes Gouvêa, Mario Guimarães Pessoa, Edson Abdala, Debora Raquel Benedita Terrabuio, Idessania Nazareth da Costa, Fabiana Martins de Paula, Ronaldo Cesar Borges Gryschek

引用次数: 0

Abstract

Immunosuppressed patients, particularly transplant recipients, can develop severe strongyloidiasis. This study aimed to detect anti-Strongyloides IgG antibodies in a panel of sera from liver transplant patients. Two techniques were used: ELISA as the initial screening test and Western blotting as a confirmatory test. ELISA reactivity of 10.9% (32/294) was observed. The 40-30 kDa fraction was recognised in 93.7% (30/32) of the patients, resulting in a positivity rate of 10.2%. These data highlight the importance of serological screening for Strongyloides stercoralis infection in liver transplant recipients.

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在肝移植受者血清中检测到抗链尾丝虫抗体：筛查这种被忽视的蠕虫病的必要性。

免疫抑制患者，尤其是器官移植受者，可能会患上严重的强直性脊柱炎。本研究旨在检测肝移植患者血清中的抗强直丝虫 IgG 抗体。研究采用了两种技术：酶联免疫吸附试验（ELISA）作为初筛试验，西方印迹法（Western blotting）作为确证试验。ELISA反应性为10.9%（32/294）。93.7% 的患者（30/32）能识别 40-30 kDa 部分，阳性率为 10.2%。这些数据凸显了在肝移植受者中进行斯特龙线虫感染血清学筛查的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Parasite Immunology 医学-寄生虫学

CiteScore

4.70

自引率

4.50%

发文量

审稿时长

6-12 weeks

期刊介绍： Parasite Immunology is an international journal devoted to research on all aspects of parasite immunology in human and animal hosts. Emphasis has been placed on how hosts control parasites, and the immunopathological reactions which take place in the course of parasitic infections. The Journal welcomes original work on all parasites, particularly human parasitology, helminths, protozoa and ectoparasites.