Conducting Nickel Hydroxide Thin Film on Molybdenum Disulfide – Reduced Graphene Oxide Composite Electrode for Simultaneous Detection of Uric Acid, Dopamine and Ascorbic Acid

IF 3.5 4区化学 Q2 ELECTROCHEMISTRY

ChemElectroChem Pub Date : 2024-07-18 DOI:10.1002/celc.202400149

Dr. Charles Luhana, Prof. Philani Mashazi

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Abstract

Herein we report the fabrication of a simple electrochemical sensor based on an electrode containing reduced graphene oxide and molybdenum disulphide (RGO/MoS₂) as a conducting film onto the glassy carbon electrode (GCE) via a drop dry method to form GCE-RGO/MoS₂. The surface (GCE-RGO/MoS₂) was further modified with nickel hydroxide thin film using electrodeposition method to form GCE-RGO/MoS₂/Ni(OH)₂. The materials and modification steps were thoroughly characterized using microscopy and spectroscopy methods. The composite electrode, GCE-RGO/MoS₂/Ni(OH)₂, showed excellent electrocatalytic potential separation for the detection of dopamine, uric acid, and ascorbic acid. The electrocatalytic oxidation peak potentials were at 3 mV, 157 mV and 303 mV for AA, DA and UA, respectively. The composite electrode was also selective towards the determination of ascorbic acid (AA), dopamine (DA), uric acid (UA), and simultaneously in mixture of analytes. The low detection limits for AA, DA and UA were 1.17 μM, 0.15 μM and 1.15 μM, respectively. The composite electrode was applied for the detection of AA, DA and UA in spiked newborn calf serum samples with high percentage recoveries ranging from 96.6–100.8 % for AA, 92.8–104.2 % for DA and 99.4–102.3 % for UA.

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二硫化钼-还原石墨烯氧化物复合电极上的导电氢氧化镍薄膜用于同时检测尿酸、多巴胺和抗坏血酸

在此，我们报告了一种基于电极的简单电化学传感器的制作方法，该电极含有还原氧化石墨烯和二硫化钼（RGO/MoS2），通过滴干法在玻璃碳电极（GCE）上形成导电薄膜 GCE-RGO/MoS2。采用电沉积法进一步用氢氧化镍薄膜修饰表面（GCE-RGO/MoS2），形成 GCE-RGO/MoS2/Ni(OH)2。使用显微镜和光谱方法对材料和改性步骤进行了全面表征。GCE-RGO/MoS2/Ni(OH)2 复合电极在多巴胺、尿酸和抗坏血酸的检测中表现出优异的电催化电位分离性能。AA、DA 和 UA 的电催化氧化峰电位分别为 3 mV、157 mV 和 303 mV。该复合电极对抗坏血酸（AA）、多巴胺（DA）和尿酸（UA）的测定也具有选择性，并能同时测定多种分析物的混合物。AA、DA 和 UA 的低检测限分别为 1.17 μM、0.15 μM 和 1.15 μM。应用该复合电极检测了添加剂新生小牛血清样品中的 AA、DA 和 UA，AA、DA 和 UA 的回收率分别为 96.6%-100.8%、92.8%-104.2% 和 99.4%-102.3%。

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来源期刊

ChemElectroChem ELECTROCHEMISTRY-

CiteScore

7.90

自引率

2.50%

发文量

515

审稿时长

1.2 months

期刊介绍： ChemElectroChem is aimed to become a top-ranking electrochemistry journal for primary research papers and critical secondary information from authors across the world. The journal covers the entire scope of pure and applied electrochemistry, the latter encompassing (among others) energy applications, electrochemistry at interfaces (including surfaces), photoelectrochemistry and bioelectrochemistry.