M Caroprese, L Cella, A Barillaro, C Oliviero, S Clemente, P Mainenti, R Pacelli, M Conson
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引用次数: 0
Abstract
Presented here is a case report of a 77-year-old woman affected by rheumatoid arthritis (RA) who underwent breast-conserving surgery followed by radiation therapy (RT) for left-breast cancer and developed bronchiolitis obliterans organizing pneumonia (BOOP) after RT and during COVID-19 vaccination campaign. BOOP incidence is an uncommon morbidity after breast RT (1.2-2.9%), however, specific predisposing factors can play a role. In this patient, both, RA and vaccine may have predisposed her to an increased risk of organizing pneumonia, probably by triggering a pro-inflammatory cascade. Our report highlights the importance of factors that influence the occurrence of uncommon radiation induced morbidities such as BOOP in specific subsets of patients. Further studies are necessary to evaluate factors increasing radiation sensitivity.
期刊介绍:
The overarching mission of Practical Radiation Oncology is to improve the quality of radiation oncology practice. PRO''s purpose is to document the state of current practice, providing background for those in training and continuing education for practitioners, through discussion and illustration of new techniques, evaluation of current practices, and publication of case reports. PRO strives to provide its readers content that emphasizes knowledge "with a purpose." The content of PRO includes:
Original articles focusing on patient safety, quality measurement, or quality improvement initiatives
Original articles focusing on imaging, contouring, target delineation, simulation, treatment planning, immobilization, organ motion, and other practical issues
ASTRO guidelines, position papers, and consensus statements
Essays that highlight enriching personal experiences in caring for cancer patients and their families.