Psychological impact of life events in systemic lupus erythematosus patients - Differences between flares and remission.

IF 1.9 4区 医学 Q3 RHEUMATOLOGY
Lupus Pub Date : 2024-09-01 Epub Date: 2024-07-21 DOI:10.1177/09612033241266987
Raquel Faria, Daniel Guimarães de Oliveira, Rute Alves, Fátima Farinha, Paulo Pinho Costa, Carlos Vasconcelos, Margarida Figueiredo-Braga
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引用次数: 0

Abstract

Background: Stress has been linked to worsening symptoms and increased disease activity in patients with Systemic lupus erythematosus (SLE). Life-events are individual stress points, and there is conflicting evidence regarding their role in SLE activity and disease perception.

Methods: Adult SLE patients were recruited for the study. Clinical and laboratory features of SLE were recorded, and previous diagnosis of anxiety or depression were retrieved from patients' electronic charts. Flares were defined by the Systemic Lupus Erythematosus Disease Activity (SLEDAI) flare Index, and flares during the previous year were documented. During a routine visit, they completed validated Portuguese translations of the 10-item Perceived Stress Scale (PSS-10), Hospital Anxiety and Depression Scale (HADS) and Life Experience Survey (LES) for the previous year.

Results: A total of 47 female SLE patients were recruited. Ten patients (21.3%) had experienced recent flares. Patients with recent flares reported fewer life events, with lower positive, negative, and total weightings sums compared to those without recent flares. Although 42.2% of patients perceived pathological levels of stress in the previous month, 48.9% had anxiety symptoms, and 34% were at high risk for an anxiety disorder, these psychometric measures did not differ significantly between the recent flare and no-flare groups.

Conclusions: There is a high prevalence of pathological levels of stress among SLE patients. SLE patients with recent flares report less psychological impact from life events, both positive and negative, independent of other psychological or pharmacological factors.

系统性红斑狼疮患者生活事件的心理影响--发作期与缓解期的差异。
背景:压力与系统性红斑狼疮(SLE)患者症状恶化和疾病活动增加有关。生活事件是个别的压力点,关于它们在系统性红斑狼疮活动和疾病感知中的作用,存在相互矛盾的证据:研究招募了成年系统性红斑狼疮患者。研究记录了系统性红斑狼疮的临床和实验室特征,并从患者的电子病历中检索了之前的焦虑或抑郁诊断。根据系统性红斑狼疮疾病活动指数(SLEDAI)定义病情发作,并记录前一年的病情发作情况。在例行就诊时,她们填写了前一年的10项感知压力量表(PSS-10)、医院焦虑抑郁量表(HADS)和生活体验调查(LES)的葡萄牙语有效译文:共招募了 47 名女性系统性红斑狼疮患者。10名患者(21.3%)近期病情曾复发。与近期没有复发的患者相比,近期复发的患者报告的生活事件较少,其积极、消极和总和的权重也较低。虽然有42.2%的患者在上个月认为压力达到了病态水平,48.9%的患者有焦虑症状,34%的患者处于焦虑症的高风险期,但这些心理测量指标在近期复发组和未复发组之间没有显著差异:结论:在系统性红斑狼疮患者中,病理性压力水平的发病率很高。结论:在系统性红斑狼疮患者中,病态压力水平的发生率很高。最近病情发作的系统性红斑狼疮患者报告说,生活事件对他们的心理影响较小,无论是积极的还是消极的,这与其他心理或药物因素无关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Lupus
Lupus 医学-风湿病学
CiteScore
4.20
自引率
11.50%
发文量
225
审稿时长
1 months
期刊介绍: The only fully peer reviewed international journal devoted exclusively to lupus (and related disease) research. Lupus includes the most promising new clinical and laboratory-based studies from leading specialists in all lupus-related disciplines. Invaluable reading, with extended coverage, lupus-related disciplines include: Rheumatology, Dermatology, Immunology, Obstetrics, Psychiatry and Cardiovascular Research…
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