Evaluation of Bone Markers in Type 2 Diabetes Mellitus.

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL

Annals of African Medicine Pub Date : 2024-07-01 Epub Date: 2024-07-20 DOI:10.4103/aam.aam_71_23

Harjeet Singh, Visesh Kumar, Ajay Kumar Singh, Surbhi Chaudhary

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引用次数: 0

Abstract

Background: Diabetes mellitus (DM) has affected over 387 million patients globally, expected to reach 592 million by the end of 2035. It is a metabolic disorder characterized by chronic hyperglycemia caused by either insulin deficiency, insulin resistance, or both.

Materials and methods: The present study was designed to estimate the levels of different bone markers; serum Vitamin D, alkaline phosphatase, phosphorus, and calcium in patients with type 2 DM (T2DM). The study was conducted on patients aged 20-50 years diagnosed with T2DM, who were attending the outpatient/inpatient department of internal medicine.

Results: The levels of calcium were decreased in the patients with diabetes and also the study proved a negative correlation between calcium and random plasma glucose (RPG). There was a significant negative correlation between RPG and serum 25(OH)D3.

Conclusion: We conclude that Vitamin D insufficiency is frequent in Moradabad, Uttar Pradesh. Sunshine exposure daily for 15 min on the face and hands is necessary to elevate the sunlight Vitamin D levels.

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评估 2 型糖尿病患者的骨标记物。

背景：全球糖尿病（DM）患者已超过 3.87 亿，预计到 2035 年底将达到 5.92 亿。糖尿病是一种代谢性疾病，其特点是由于胰岛素缺乏、胰岛素抵抗或两者兼而有之而导致的慢性高血糖：本研究旨在估测 2 型糖尿病（T2DM）患者的不同骨标记物（血清维生素 D、碱性磷酸酶、磷和钙）水平。研究对象是在内科门诊/住院部就诊的 20-50 岁确诊为 T2DM 的患者：结果：糖尿病患者体内的钙水平下降，研究还证明钙与随机血浆葡萄糖（RPG）之间存在负相关。随机血浆葡萄糖与血清 25(OH)D3 呈明显负相关：我们得出结论，北方邦莫拉达巴德地区经常出现维生素 D 不足的情况。每天在阳光下照射脸部和手部 15 分钟对提高日光维生素 D 水平很有必要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of African Medicine MEDICINE, GENERAL & INTERNAL-

CiteScore

0.90

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0.00%

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期刊介绍： The Annals of African Medicine is published by the Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria and the Annals of African Medicine Society. The Journal is intended to serve as a medium for the publication of research findings in the broad field of Medicine in Africa and other developing countries, and elsewhere which have relevance to Africa. It will serve as a source of information on the state of the art of Medicine in Africa, for continuing education for doctors in Africa and other developing countries, and also for the publication of meetings and conferences. The journal will publish articles I any field of Medicine and other fields which have relevance or implications for Medicine.