Characteristics of Stroke-related Seizures and their Predictive Factors: A Tertiary Care Center Experience.

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL

Annals of African Medicine Pub Date : 2024-07-01 Epub Date: 2024-07-20 DOI:10.4103/aam.aam_15_23

Erum Shariff, Saima Nazish, Azra Zafar, Rizwana Shahid, Danah Aljaafari, Nehad Mahmoud Soltan, Ahmed Mohamed Farhan, Fahd A Alkhamis, Mohammed AlShurem, Osama Faisal Hassan Basheir, Foziah Alshamrani, Aishah Ibrahim Albakr, Omar Al Ghamdi, Abdulla A AlSulaiman, Majed Al Abdali

{"title":"Characteristics of Stroke-related Seizures and their Predictive Factors: A Tertiary Care Center Experience.","authors":"Erum Shariff, Saima Nazish, Azra Zafar, Rizwana Shahid, Danah Aljaafari, Nehad Mahmoud Soltan, Ahmed Mohamed Farhan, Fahd A Alkhamis, Mohammed AlShurem, Osama Faisal Hassan Basheir, Foziah Alshamrani, Aishah Ibrahim Albakr, Omar Al Ghamdi, Abdulla A AlSulaiman, Majed Al Abdali","doi":"10.4103/aam.aam_15_23","DOIUrl":null,"url":null,"abstract":"Background and purpose: Various risk factors have been described in the literature that increase the risk of seizures associated with stroke. This study was aimed to determine the occurrence rate of poststroke seizures (PSSs) and the associated risk factors in Arab population.Materials and methods: Study included all stroke patients aged >18 years with a minimum follow-up of 24 months following stroke to identify seizure occurrence. Patient's hospital records for all admissions and clinic visits were reviewed. Seizures were classified into early PSS if they occur within 1 week of stroke, and late PSS if they occur after 1 week of stroke.Results: Out of 594 patients, 380 were males. Seizure occurrence was higher in anterior circulation infarctions (94.8%, P < 0.05), cortical location (80.5%, P < 0.05), large artery atherosclerosis (63.8%, P < 0.05), lower activated partial thromboplastin time (APTT) (P = 0.0007), patients with ischemic heart disease (IHD) (P = 0.01), and those who underwent craniotomy (P = 0.001). Nonhigh-density lipoprotein cholesterol was inversely related to PSS (P = 0.01). Higher stroke severity (89%) and confusion (67%) at the time of presentation were independently related to PSS.Conclusions: Eighty-two (13.8%) patients had PSS. Greater stroke severity at presentation with altered sensorium was independent risk factors for the development of PSS. Patients with underlying IHD, lower APTT, and undergoing neurosurgical intervention require vigilant monitoring for PSS.","PeriodicalId":7938,"journal":{"name":"Annals of African Medicine","volume":"23 3","pages":"285-290"},"PeriodicalIF":0.6000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11364308/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of African Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/aam.aam_15_23","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/7/20 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

Abstract

Background and purpose: Various risk factors have been described in the literature that increase the risk of seizures associated with stroke. This study was aimed to determine the occurrence rate of poststroke seizures (PSSs) and the associated risk factors in Arab population.

Materials and methods: Study included all stroke patients aged >18 years with a minimum follow-up of 24 months following stroke to identify seizure occurrence. Patient's hospital records for all admissions and clinic visits were reviewed. Seizures were classified into early PSS if they occur within 1 week of stroke, and late PSS if they occur after 1 week of stroke.

Results: Out of 594 patients, 380 were males. Seizure occurrence was higher in anterior circulation infarctions (94.8%, P < 0.05), cortical location (80.5%, P < 0.05), large artery atherosclerosis (63.8%, P < 0.05), lower activated partial thromboplastin time (APTT) (P = 0.0007), patients with ischemic heart disease (IHD) (P = 0.01), and those who underwent craniotomy (P = 0.001). Nonhigh-density lipoprotein cholesterol was inversely related to PSS (P = 0.01). Higher stroke severity (89%) and confusion (67%) at the time of presentation were independently related to PSS.

Conclusions: Eighty-two (13.8%) patients had PSS. Greater stroke severity at presentation with altered sensorium was independent risk factors for the development of PSS. Patients with underlying IHD, lower APTT, and undergoing neurosurgical intervention require vigilant monitoring for PSS.

查看原文本刊更多论文

脑卒中相关癫痫发作的特征及其预测因素：三级医疗中心的经验

背景和目的：文献中描述了各种增加中风相关癫痫发作风险的风险因素。本研究旨在确定阿拉伯人群卒中后癫痫发作（PSSs）的发生率及相关风险因素：研究对象包括所有年龄大于 18 岁、在中风后至少随访 24 个月的中风患者，以确定癫痫发作情况。研究审查了患者的所有住院和门诊记录。如果癫痫发作发生在脑卒中后 1 周内，则将其分为早期 PSS；如果发生在脑卒中后 1 周后，则将其分为晚期 PSS：结果：594 名患者中有 380 名男性。前循环梗死（94.8%，P＜0.05）、皮质位置（80.5%，P＜0.05）、大动脉粥样硬化（63.8%，P＜0.05）、活化部分凝血活酶时间（APTT）较低（P＝0.0007）、缺血性心脏病（IHD）患者（P＝0.01）和开颅手术患者（P＝0.001）的癫痫发作率较高。非高密度脂蛋白胆固醇与 PSS 呈反比关系（P = 0.01）。卒中严重程度较高（89%）和发病时意识模糊（67%）与 PSS 独立相关：结论：82 名患者（13.8%）患有 PSS。结论：82 名患者（13.8%）罹患 PSS。发病时中风严重程度更高且感觉改变是发生 PSS 的独立风险因素。患有基础性 IHD、APTT 较低以及接受神经外科干预的患者需要警惕 PSS。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Annals of African Medicine MEDICINE, GENERAL & INTERNAL-

CiteScore

0.90

自引率

0.00%

发文量

期刊介绍： The Annals of African Medicine is published by the Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria and the Annals of African Medicine Society. The Journal is intended to serve as a medium for the publication of research findings in the broad field of Medicine in Africa and other developing countries, and elsewhere which have relevance to Africa. It will serve as a source of information on the state of the art of Medicine in Africa, for continuing education for doctors in Africa and other developing countries, and also for the publication of meetings and conferences. The journal will publish articles I any field of Medicine and other fields which have relevance or implications for Medicine.