Drug utilization reviews to reduce inappropriate drug use and pharmaceutical costs in inpatients based on diagnosis-related group data.

IF 1.4 4区 医学 Q4 ENGINEERING, BIOMEDICAL
Wei Tian, Sheng Zhang, Yuan Gao, Yan Wang, Qianqian Cui
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引用次数: 0

Abstract

Background: Irrational pharmacotherapy and increasing pharmacy costs remain major concerns in healthcare systems. Pharmacists are expected to employ diagnosis-related group (DRG) data to analyse inpatient pharmacy utilization.

Objective: This project aimed to pilot an efficient pharmacist-led programme to analyse factors related to pharmacy expenses, evaluate the rational use of drugs in batch processing, and make further interventions based on DRG data.

Methods: Patients from the OB25 (caesarean section without comorbidities or complications) DRG were selected in 2018, and the most relevant factors were identified through statistical analysis. Interventions were implemented by sending monthly reports on prescribing data and drug review results for the same DRGs to the department starting in 2019. Pre-post comparisons were conducted to demonstrate changes in pharmacy costs and appropriateness at a tertiary teaching hospital with 2,300 beds in China.

Results: A total of 1,110 patients were identified from the OB25 DRG data in 2018. Multivariate linear analysis indicated that the number of items prescribed and wards substantially influenced pharmacy expenditure. Drugs labelled as vital, essential, and non-essential revealed that 46.6% of total pharmacy costs were spent on non-essential drugs, whereas 38.7% were spent on vital drugs. The use of inappropriate pharmaceuticals and drug items was substantially reduced, and the average pharmacy cost after intervention was 336.7 RMB in 2020. The benefit-cost ratio of the programme was 9.86.

Conclusion: Interventions based on DRG data are highly efficient and feasible for reducing inpatient pharmacy costs and non-essential drug use.

根据诊断相关组数据,对药物使用情况进行审查,以减少住院病人的不当用药和医药费用。
背景:不合理的药物治疗和不断增加的药房成本仍然是医疗系统的主要问题。药剂师应利用诊断相关分组(DRG)数据分析住院病人的药房使用情况:本项目旨在试行一项以药剂师为主导的高效计划,分析与药房费用相关的因素,评估批量处理中药物的合理使用情况,并根据 DRG 数据采取进一步干预措施:选取2018年OB25(无合并症或并发症的剖腹产)DRG中的患者,通过统计分析找出最相关的因素。从2019年开始,每月向科室发送相同DRGs的处方数据报告和药物审查结果,实施干预措施。在中国一家拥有 2300 张病床的三级教学医院中,进行了前后比较,以展示药房成本和合理性的变化:2018 年,从 OB25 DRG 数据中共识别出 1110 名患者。多变量线性分析表明,处方项目数和病房对药费支出有很大影响。标记为重要、必需和非必需的药物显示,药房总成本的 46.6% 花在了非必需药物上,而 38.7% 花在了重要药物上。不适当药品和药品项目的使用大幅减少,2020 年干预后的平均药房成本为 336.7 元人民币。方案的效益成本比为 9.86:基于 DRG 数据的干预措施在降低住院药房成本和非基本药物使用方面是高效可行的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Technology and Health Care
Technology and Health Care HEALTH CARE SCIENCES & SERVICES-ENGINEERING, BIOMEDICAL
CiteScore
2.10
自引率
6.20%
发文量
282
审稿时长
>12 weeks
期刊介绍: Technology and Health Care is intended to serve as a forum for the presentation of original articles and technical notes, observing rigorous scientific standards. Furthermore, upon invitation, reviews, tutorials, discussion papers and minisymposia are featured. The main focus of THC is related to the overlapping areas of engineering and medicine. The following types of contributions are considered: 1.Original articles: New concepts, procedures and devices associated with the use of technology in medical research and clinical practice are presented to a readership with a widespread background in engineering and/or medicine. In particular, the clinical benefit deriving from the application of engineering methods and devices in clinical medicine should be demonstrated. Typically, full length original contributions have a length of 4000 words, thereby taking duly into account figures and tables. 2.Technical Notes and Short Communications: Technical Notes relate to novel technical developments with relevance for clinical medicine. In Short Communications, clinical applications are shortly described. 3.Both Technical Notes and Short Communications typically have a length of 1500 words. Reviews and Tutorials (upon invitation only): Tutorial and educational articles for persons with a primarily medical background on principles of engineering with particular significance for biomedical applications and vice versa are presented. The Editorial Board is responsible for the selection of topics. 4.Minisymposia (upon invitation only): Under the leadership of a Special Editor, controversial or important issues relating to health care are highlighted and discussed by various authors. 5.Letters to the Editors: Discussions or short statements (not indexed).
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