The Influence of Polysaccharide Fractions of the Lion’s Mane Medicinal Mushroom Hericium erinaceus (Agaricomycetes) on the Immunomodulatory and Antioxidant Activity of Neutrophils Exposed to Stress of Different Durations

IF 1.4 4区生物学 Q4 MYCOLOGY

International journal of medicinal mushrooms Pub Date : 2024-07-01 DOI:10.1615/intjmedmushrooms.2024054937

Oksana Zaitseva, Marta Sergushkina, Dmitry Popyvanov, Yanina Nazarova, Tatyana Polezhaeva, Olga Solomina, Andrey Khudyakov

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引用次数: 0

Abstract

Polysaccharide fractions from the mycelium of the fungus Hericium erinaceus BP 16, cultivated on sterile grain substrates (barley, oats, wheat, rice, rye), were isolated and characterized. 1% solutions were prepared from the resulting fractions, mixed with a blood, which was then subjected to cold stress at a temperature of 6°C for 3, 5 and 7 days. It has been shown that the fraction of H. erinaceus grown on rye is characterized by a high content of the protein fraction and arabinose monosaccharide and contributes to the preservation of higher phagocytic, bactericidal and antioxidant activity cells throughout the entire period of stress. Polysaccharide fractions of the fungus H. erinaceus, grown on various grain substrates, can serve as an immunomodulatory and antioxidant food additive and provide significant benefits in the daily life of people with stress and reduced immunity.

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狮鬃草（姬松茸）多糖组分对暴露于不同持续时间应激的中性粒细胞的免疫调节和抗氧化活性的影响

从在无菌谷物基质（大麦、燕麦、小麦、大米、黑麦）上培养的真菌 Hericium erinaceus BP 16 菌丝体中分离出多糖组分并对其进行表征。从得到的馏分中制备出 1%的溶液，与血液混合，然后在 6°C 的温度下进行 3、5 和 7 天的冷应激。研究表明，在黑麦上生长的麦角菌的馏分具有蛋白质馏分和阿拉伯糖单糖含量高的特点，有助于在整个应激期间保持较高的吞噬、杀菌和抗氧化活性细胞。在各种谷物基质上生长的真菌麦角菌的多糖部分可作为一种免疫调节和抗氧化食品添加剂，为压力和免疫力下降人群的日常生活带来显著益处。

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来源期刊

International journal of medicinal mushrooms 医学-药学

CiteScore

2.60

自引率

16.70%

发文量

审稿时长

6-12 weeks

期刊介绍： The rapid growth of interest in medicinal mushrooms research is matched by the large number of disparate groups that currently publish in a wide range of publications. The International Journal of Medicinal Mushrooms is the one source of information that will draw together all aspects of this exciting and expanding field - a source that will keep you up to date with the latest issues and practice. The International Journal of Medicinal Mushrooms published original research articles and critical reviews on a broad range of subjects pertaining to medicinal mushrooms, including systematics, nomenclature, taxonomy, morphology, medicinal value, biotechnology, and much more.