Efficacy and safety of wet cupping in the management of Gout: An open labeled, randomized standard control study

IF 1.7 Q2 Medicine
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引用次数: 0

Abstract

Background

The most prevalent form of inflammatory arthritis is Gouty arthritis. Wet cupping, a traditional regimental therapy of Greco-Arab and Chinese medicine, has been proven an effective and safe alternative treatment for multiple disorders especially in musculoskeletal ailments.

Aims and objectives

To study the efficacy and safety of wet cupping in Gouty arthritis.

Methods

In an open-labeled, randomized and standard controlled trial 60 patients of gout fulfilling the inclusion criteria were randomly allocated in test group (n=30) receiving wet cupping and the control group (n=30) receiving allopurinol for a period of 60 days. Patients were assessed at every 15th day for subjective parameters/symptoms, whereas for objective parameters (serum uric acid, inflammatory markers) assessment was done at 0th day and on 61st day of the study protocol. The data was analyzed statistically using student t-test to obtain the results.

Results

Both the test and control groups showed a significant improvement in subjective parameters (p<0.001). Serum uric acid gets significantly improved after the treatment (p<0.001) in both the groups, however among inflammatory markers, better improvement in ESR was seen in test group (p< 0.05) than control group (p=0.37) but there was no considerable improvement in CRP either in test or control group. All the safety parameters (LFT, KFT) were found to remain undisturbed after completion of study protocol.

Conclusion

Wet cupping has a considerable impact in improving the symptoms of gout and serum uric acid levels. It is much safer and could prove a better alternative for gout management.

湿拔罐治疗痛风的有效性和安全性:开放标签、随机标准对照研究
背景 痛风性关节炎是炎症性关节炎中最常见的一种。方法在一项开放标签、随机和标准对照试验中,60 名符合纳入标准的痛风患者被随机分配到试验组(30 人)和对照组(30 人),试验组接受湿拔罐治疗,对照组接受别嘌呤醇治疗,为期 60 天。每隔 15 天对患者的主观参数/症状进行评估,而客观参数(血清尿酸、炎症指标)评估则在研究方案的第 0 天和第 61 天进行。结果试验组和对照组的主观指标均有显著改善(p<0.001)。两组治疗后血清尿酸均有明显改善(p<0.001),但在炎症指标中,试验组的血沉(p<0.05)比对照组有更好的改善(p=0.37),但试验组和对照组的 CRP 均无明显改善。所有安全参数(低密度脂蛋白胆固醇、高密度脂蛋白胆固醇)在研究方案完成后均保持不变。湿拔罐在改善痛风症状和血清尿酸水平方面效果显著,而且更加安全,可以证明是治疗痛风的一种更好的替代方法。
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来源期刊
Advances in integrative medicine
Advances in integrative medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-
CiteScore
3.20
自引率
11.80%
发文量
0
审稿时长
15 weeks
期刊介绍: Advances in Integrative Medicine (AIMED) is an international peer-reviewed, evidence-based research and review journal that is multi-disciplinary within the fields of Integrative and Complementary Medicine. The journal focuses on rigorous quantitative and qualitative research including systematic reviews, clinical trials and surveys, whilst also welcoming medical hypotheses and clinically-relevant articles and case studies disclosing practical learning tools for the consulting practitioner. By promoting research and practice excellence in the field, and cross collaboration between relevant practitioner groups and associations, the journal aims to advance the practice of IM, identify areas for future research, and improve patient health outcomes. International networking is encouraged through clinical innovation, the establishment of best practice and by providing opportunities for cooperation between organisations and communities.
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