Glans cap-preserving dorsal inlay-free graft augmentation technique for reconstruction of meatal stenosis and fossa navicularis strictures: Analysis of short-term functional outcomes

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
B. Enganti, Prashant A. Nanavati, V. Madduri, Amish Wani, Mallikarjuna Chiruvella
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引用次数: 0

Abstract

Meatal stenosis and fossa navicularis strictures (FNSs) are commonly caused by lichen sclerosus and instrumentation. We present the technique and short-term functional outcomes of glans cap-preserving dorsal inlay-free graft augmentation for the reconstruction of meatal stenosis and FNS. This retrospective study analyzed patients with meatal stenosis and FNS who underwent glans cap-preserving dorsal inlay-free graft augmentation at our institute since 2019. The surgical technique included a ventral subcoronal approach, preservation and mobilization of the glans cap, a ventral midline urethrotomy incision over the stricture, and a dorsal midline meatotomy incision extending to the proximal normal urethral mucosa at the fossa navicularis, followed by dorsal inlay graft augmentation. During the follow-up, patients were periodically assessed for symptom scores, urinary flow rates (UFRs), and patient-reported outcomes. A total of 26 patients with a mean age of 45 ± 15 years were assessed. The predominant cause of stricture was lichen sclerosus (n = 15; 58%). The mean stricture length was 3.8 ± 0.5 cm, 73% had a circumcised phallus, and an oral mucosa graft augmentation was performed in 22 (85%) patients. Notable postoperative complications included intractable meatal hemorrhage (n = 1) and glans suture granuloma (n = 1), which required intervention. At a mean follow-up of 40 months, there were four failures, of which one patient required redo-urethroplasty. The remaining patients (n = 22; 85%) showed improved symptom scores (P < 0.05), UFRs (P < 0.05), and satisfactory patient-reported outcomes. Glans cap-preserving dorsal inlay-free graft augmentation is a safe and feasible technique with satisfactory short-term functional outcomes for the management of meatal stenosis and FNS in carefully selected patients.
用于重建肉腔狭窄和舟状窝狭窄的龟头帽保留背侧无嵌体移植增高技术:短期功能效果分析
肉腔狭窄和舟状窝狭窄(FNS)通常是由硬皮病和器械操作引起的。我们介绍了保留龟头帽的背侧无嵌体移植物增殖术重建肉阜狭窄和 FNS 的技术和短期功能效果。 这项回顾性研究分析了自2019年以来在我院接受龟头帽保留背侧无嵌体移植物增大术的肉阜狭窄和FNS患者。手术方法包括腹侧冠状沟下入路、保留并移动龟头帽、在狭窄处行腹侧中线尿道切开术、背侧中线肉膜切开术,延伸至舟骨窝处的近端正常尿道粘膜,然后进行背侧无嵌体植皮增粗术。在随访期间,定期对患者的症状评分、尿流率(UFR)和患者报告结果进行评估。 共对 26 名患者进行了评估,他们的平均年龄为 45 ± 15 岁。造成狭窄的主要原因是硬化性苔藓(n = 15;58%)。狭窄的平均长度为 3.8 ± 0.5 厘米,73% 的患者阴茎包皮过长,22 名患者(85%)进行了口腔黏膜移植增殖术。值得注意的术后并发症包括难治性肉腔出血(1 例)和龟头缝合肉芽肿(1 例),需要进行干预。在平均 40 个月的随访中,有四例手术失败,其中一名患者需要重新进行尿道成形术。其余患者(n = 22;85%)的症状评分(P < 0.05)、UFR(P < 0.05)和患者报告结果均有所改善。 龟头帽保留背侧无嵌体移植增高术是一种安全可行的技术,在治疗经仔细挑选的肉阜狭窄和 FNS 患者时,短期功能效果令人满意。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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