APACHE-adjusted ICU Outcomes Have Returned to Pre-pandemic Values

Thomas Higgins, Eric Ringle, K. Henson
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Abstract

During the COVID-19 pandemic, severity-adjustment systems lacked longitudinal data for the coronavirus and thus could not specify diagnosis-specific risk. Without risk adjustment for the patient’s diagnosis and presenting condition, outcomes such as morbidity, mortality, and length of stay become challenging to interpret. APACHE, which risk-adjusts for acute physiology, age, and chronic health, is a widely used ICU benchmarking tool, and participating institutions identified rising and concerning standardized mortality rates in 2020. Following up on previously reported results that severity-adjusted outcomes were worse than expected for patients with COVID-19 versus traditional viral pneumonia during the first two years of the pandemic, the authors now report data that suggest the COVID-19 mortality penalty versus other viral pneumonia lessened once the Omicron variant became the predominant pathogen in early 2022. They present implications for benchmarking hospital performance and public reporting.
经 APACHE 调整的重症监护室结果已恢复到大流行前的数值
在 COVID-19 大流行期间,严重程度调整系统缺乏冠状病毒的纵向数据,因此无法明确诊断特定风险。如果不对患者的诊断和病情进行风险调整,就很难解释发病率、死亡率和住院时间等结果。根据急性生理学、年龄和慢性疾病进行风险调整的 APACHE 是一种广泛使用的 ICU 基准工具,参与机构发现 2020 年的标准化死亡率不断上升,令人担忧。此前有报道称,在大流行的前两年,COVID-19 与传统病毒性肺炎患者相比,严重程度调整后的治疗效果比预期的要差,作者现在报告的数据表明,一旦 2022 年初 Omicron 变体成为主要病原体,COVID-19 与其他病毒性肺炎相比的死亡率惩罚就会减轻。他们提出了医院绩效基准和公共报告的意义。
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