Impact of coffee and its bioactive compounds on the risks of type 2 diabetes and its complications: A comprehensive review

IF 4.3 Q1 ENDOCRINOLOGY & METABOLISM
Almahi I. Mohamed , Ochuko L. Erukainure , Veronica F. Salau , Md Shahidul Islam
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引用次数: 0

Abstract

Background

Coffee beans have a long history of use as traditional medicine by various indigenous people. Recent focus has been given to the health benefits of coffee beans and its bioactive compounds. Research on the bioactivities, applications, and effects of processing methods on coffee beans' phytochemical composition and activities has been conducted extensively. The current review attempts to provide an update on the biological effects of coffee on type 2 diabetes (T2D) and its comorbidities.

Methods

Comprehensive literature search was carried out on peer-reviewed published data on biological activities of coffee on in vitro, in vivo and epidemiological research results published from January 2015 to December 2022, using online databases such as PubMed, Google Scholar and ScienceDirect for our searches.

Results

The main findings were: firstly, coffee may contribute to the prevention of oxidative stress and T2D-related illnesses such as cardiovascular disease, retinopathy, obesity, and metabolic syndrome; secondly, consuming up to 400 mg/day (1–4 cups per day) of coffee is associated with lower risks of T2D; thirdly, caffeine consumed between 0.5 and 4 h before a meal may inhibit acute metabolic rate; and finally, both caffeinated and decaffeinated coffee are associated with reducing the risks of T2D.

Conclusion

Available evidence indicates that long-term consumption of coffee is associated with decreased risk of T2D and its complications as well as decreased body weight. This has been attributed to the consumption of coffee with the abundance of bioactive chemicals.

咖啡及其生物活性化合物对 2 型糖尿病及其并发症风险的影响:全面综述
背景咖啡豆被各种原住民用作传统药物的历史悠久。最近,人们开始关注咖啡豆及其生物活性化合物对健康的益处。有关咖啡豆的生物活性、应用以及加工方法对其植物化学成分和活性的影响的研究已广泛开展。本综述试图就咖啡对 2 型糖尿病(T2D)及其合并症的生物效应提供最新信息。方法利用 PubMed、Google Scholar 和 ScienceDirect 等在线数据库,对 2015 年 1 月至 2022 年 12 月期间发表的有关咖啡生物活性的体外、体内和流行病学研究成果的同行评审发表数据进行了全面的文献检索。结果主要发现:第一,咖啡可能有助于预防氧化应激和与 T2D 相关的疾病,如心血管疾病、视网膜病变、肥胖和代谢综合征;第二,每天摄入 400 毫克(每天 1-4 杯)咖啡与降低 T2D 风险相关;第三,餐前 0.结论现有证据表明,长期饮用咖啡可降低患 T2D 及其并发症的风险并减轻体重。这归因于饮用含有大量生物活性化学物质的咖啡。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
22.90
自引率
2.00%
发文量
248
审稿时长
51 days
期刊介绍: Diabetes and Metabolic Syndrome: Clinical Research and Reviews is the official journal of DiabetesIndia. It aims to provide a global platform for healthcare professionals, diabetes educators, and other stakeholders to submit their research on diabetes care. Types of Publications: Diabetes and Metabolic Syndrome: Clinical Research and Reviews publishes peer-reviewed original articles, reviews, short communications, case reports, letters to the Editor, and expert comments. Reviews and mini-reviews are particularly welcomed for areas within endocrinology undergoing rapid changes.
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