Relation between Thyroid Function Tests and Body Mass Index among Thyroid Dysfunction Patients

Sanaa Othman Karim, K. M. Gharib, Maisam Hama Murad Majeed, Hadeel Abdulelah Ibrahim, B. O. Sharif, Diman F. Salih, Balen F. Hamasaeed
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Abstract

Background: Obesity has the potential to impact thyroid function through various pathways, even in individuals considered euthyroid. The relationship between thyroid function and body mass index (BMI) remains a subject of ongoing debate. Therefore, the primary objective of this study was to ascertain the correlation existing among thyroid stimulating hormone (TSH), thyroid hormones, and BMI in patients experiencing thyroid dysfunction within the context of the Smart Health Tower. Methods: This cross-sectional study was conducted in Smart Health Tower in Sulaimani city from November 9, 2021, to March 1, 2022. One hundred and sixty-six patients with thyroid dysfunction (128 individuals had hypothyroidism, eight individuals had hyperthyroidism, and 30 individuals were the other type of thyroid dysfunction) were enrolled in this study. Their mean age was 43.62 ± 11.17 and 50.6% of the participation were male. Patients were divided into four groups based on BMI value: Underweight (BMI <18.5 kg/m2), normal (BMI: 18.5–24.9 kg/m2), overweight (BMI: 25–29.9 kg/m2), and obese (BMI ≥30 kg/m2). Results: The highest rate of age group was between (30 and 40) years old (84%) of them were male. The participants with higher BMI had higher TSH and this trend continued from underweight to Obese. The mean TSH of the underweight group was 0.47 ± 0.61 mIU/L, the normal weight group 1.5 ± 1.91 mIU/L, the overweight group 2.8± 3.87 mIU/L and the obese group 2.7 ± 2.37 mIU/L. Conclusion: A significant relationship between serum TSH and BMI and mean TSH increased as BMI increased. Further large-scale data from the population are required to confirm these findings.
甲状腺功能障碍患者的甲状腺功能测试与体重指数之间的关系
背景:肥胖有可能通过各种途径影响甲状腺功能,即使是被认为甲状腺功能正常的人也不例外。甲状腺功能与体重指数(BMI)之间的关系仍是一个争论不休的话题。因此,本研究的主要目的是确定智能健康塔中甲状腺功能障碍患者促甲状腺激素(TSH)、甲状腺激素和体重指数之间的相关性。研究方法这项横断面研究于 2021 年 11 月 9 日至 2022 年 3 月 1 日在苏莱曼尼市智能健康塔进行。166 名甲状腺功能障碍患者(128 人患有甲状腺功能减退症,8 人患有甲状腺功能亢进症,30 人患有其他类型的甲状腺功能障碍)被纳入本研究。他们的平均年龄为(43.62±11.17)岁,50.6%为男性。根据体重指数值将患者分为四组:体重不足(BMI<18.5 kg/m2)、正常(BMI:18.5-24.9 kg/m2)、超重(BMI:25-29.9 kg/m2)和肥胖(BMI≥30 kg/m2)。结果显示年龄在(30 至 40)岁之间的男性比例最高,占 84%。体重指数越高的参与者 TSH 越高,而且这一趋势从体重不足一直持续到肥胖。体重不足组的 TSH 平均值为 0.47 ± 0.61 mIU/L,正常体重组为 1.5 ± 1.91 mIU/L,超重组为 2.8 ± 3.87 mIU/L,肥胖组为 2.7 ± 2.37 mIU/L。结论血清促甲状腺激素与体重指数(BMI)之间存在明显关系,平均促甲状腺激素随体重指数(BMI)的升高而升高。需要进一步的大规模人群数据来证实这些发现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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