Good practice in laboratory diagnostic andrology: Association of Reproductive and Clinical Scientists guidelines 2024

IF 3.7 2区医学 Q1 OBSTETRICS & GYNECOLOGY

Reproductive biomedicine online Pub Date : 2024-07-14 DOI:10.1016/j.rbmo.2024.104373

Meurig T. Gallagher , Emily Roxburgh , Gwen Bennett , Susan Parker , Jackson C. Kirkman-Brown , Association of Reproductive and Clinical Scientists

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引用次数: 0

Abstract

These guidelines update and clarify items relating to diagnostic andrology in the 2012 Association of Biomedical Andrologists Laboratory Andrology Guidelines for Good Practice Version 3. The main change separates diagnostic and therapeutic andrology into individual documents; post-vasectomy semen analysis still references the 2016 guideline. These guidelines seek to incorporate and clarify internationally agreed methodology following the World Health Organization Laboratory Manual for the Examination and Processing of Human Semen 6th edition and publication of ISO 23162:2021. Significant updates include: requiring four-category grading for motility (A, rapidly progressive; B, slowly progressive; C, non-progressive; D, immotile); a four-part morphology assessment (head, midpiece, tail, cytoplasmic droplets) as essential for quality assurance (even if only the percentage of ‘normal’ is reported); and specifying sperm toxicity testing procedures for diagnostic andrology. These guidelines include a section on haematospermia, an observation requiring rapid onward referral. An Association of Reproductive and Clinical Scientists (ARCS) working group wrote these guidelines, with review by ARCS members. The aim is to guide good practice in laboratories but they are not intended as a tool to judge the practice of centres within the UK or beyond.

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英国实验室诊断 Andrology 良好操作指南 (2024)

本指南更新并明确了 2012 年生物医学 Andrologists 实验室 Andrology 良好实践指南第 3 版中与诊断性 Andrology 相关的项目。主要变化是将诊断性和治疗性泌尿学分为单独的文件；输精管结扎术后精液分析仍参考 2016 年指南。在世界卫生组织《人类精液检查和处理实验室手册》第 6 版和 ISO 23162:2021 发布之后，这些指南力求纳入并明确国际公认的方法。重要的更新包括：要求对精子活力进行四级分级（A 级，快速进展；B 级，缓慢进展；C 级，非进展；D 级，无活力）；将四部分形态评估（头部、中段、尾部、细胞质小滴）作为质量保证的基本要素（即使只报告 "正常 "的百分比）；并明确了诊断性睾丸炎的精子毒性检测程序。这些指南包括一个关于血精症的章节，血精症是一种需要迅速转诊的病症。生殖与临床科学家协会（ARCS）工作组编写了这些指南，并由协会成员进行了审查。其目的是为实验室的良好实践提供指导，但并不打算将其作为评判英国境内外各中心实践的工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Reproductive biomedicine online 医学-妇产科学

CiteScore

7.20

自引率

7.50%

发文量

391

审稿时长

50 days

期刊介绍： Reproductive BioMedicine Online covers the formation, growth and differentiation of the human embryo. It is intended to bring to public attention new research on biological and clinical research on human reproduction and the human embryo including relevant studies on animals. It is published by a group of scientists and clinicians working in these fields of study. Its audience comprises researchers, clinicians, practitioners, academics and patients. Context: The period of human embryonic growth covered is between the formation of the primordial germ cells in the fetus until mid-pregnancy. High quality research on lower animals is included if it helps to clarify the human situation. Studies progressing to birth and later are published if they have a direct bearing on events in the earlier stages of pregnancy.