Antibacterial and anticancer activities of cardamom volatile oil and its application in food covering

IF 4.3 3区材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC

ACS Applied Electronic Materials Pub Date : 2024-07-03 DOI:10.15586/ijfs.v36i3.2534

Tahani M. Alqahtani, Ebtisam G. R. Ebrahim, Abeer S. Aloufi, Sayed S. El-Saadany, Enas A. Almanzalawi, Ahmed Awad, Gehad S. Eldeeb, Lamiaa M. M. El-Maghraby

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引用次数: 0

Abstract

Phytochemicals and bioactive compounds in medicinal plants significantly benefit human health and well-being. Cardamom essential oil (CEO) exhibits potential as a broad-spectrum antimicrobial and anticancer agent. A modified Kirby-Bauer disc diffusion technique was used to test cardamom essential oil’s antimicrobial activity and identify the inhibition zone. Staphylococcus aureus (ATCC 6538) and Bacillus cereus (ATCC6629) are two examples of Gram-positive bacteria against which the essential oil was evaluated for antibacterial activity. Gram-negative microorganisms such as Pseudomonas aeruginosa (ATCC 27853), Escherichia coli (ATCC25922), and yeast Candida albicans were also evaluated for antimicrobial activity. The essential oil was assessed further against human liver (HEPG-2) and breast (MCF7) cell lines for anticancer properties. The findings suggest that, compared to the control, cardamom essential oil exhibits a significant zone of inhibition against all types of microbes except Pseudomonas aeruginosa. Additionally, for anti-cancer actions, the IC50 values were 42.3 µg/ml for MCF7 and 54 µg/ml for HEPG-2 cell lines, while IC90 results for MCF7 were 68.9 µg/ml and for HEPG-2 cell line were 80.7 µg/ml. The essential oil was developed in functional coating to preserve the postharvest mango fruit for 60 days at cold storage. The treated fruit showed reduced weight loss (10%), with a relative reduction of 78% compared to the control, chilling injury incidence (2.5%) at day 45, and rind pitting (3%) at day 30 compared to the control. This therapeutic plant may yield novel compounds for broad-spectrum antimicrobial and anticancer medicines and be transformed into economical and secure standardized herbal products.

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小豆蔻挥发油的抗菌和抗癌活性及其在食品覆盖中的应用

药用植物中的植物化学物质和生物活性化合物对人类的健康和福祉大有裨益。小豆蔻精油（CEO）具有广谱抗菌和抗癌的潜力。研究人员采用改良柯比-鲍尔盘扩散技术来测试小豆蔻精油的抗菌活性并确定抑菌区。对金黄色葡萄球菌（ATCC 6538）和蜡样芽孢杆菌（ATCC6629）这两种革兰氏阳性菌进行了精油抗菌活性评估。此外，还对铜绿假单胞菌（ATCC 27853）、大肠杆菌（ATCC25922）和白色念珠菌等革兰氏阴性微生物进行了抗菌活性评估。还进一步评估了精油对人类肝脏（HEPG-2）和乳腺（MCF7）细胞系的抗癌特性。研究结果表明，与对照组相比，豆蔻精油对除铜绿假单胞菌以外的所有微生物都有明显的抑制作用。此外，在抗癌作用方面，MCF7 和 HEPG-2 细胞系的 IC50 值分别为 42.3 微克/毫升和 54 微克/毫升，而 MCF7 和 HEPG-2 细胞系的 IC90 值分别为 68.9 微克/毫升和 80.7 微克/毫升。该精油被开发成功能性涂层，用于在冷库中保存采后芒果果实 60 天。与对照组相比，经处理的水果重量损失减少了 10%，相对损失率为 78%；与对照组相比，第 45 天的冷冻伤发生率减少了 2.5%；第 30 天的果皮麻点率减少了 3%。这种治疗植物可产生新型化合物，用于广谱抗菌和抗癌药物，并可转化为经济、安全的标准化草药产品。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Applied Electronic Materials Multiple-

CiteScore

7.20

自引率

4.30%

发文量

567

期刊介绍： ACS Applied Electronic Materials is an interdisciplinary journal publishing original research covering all aspects of electronic materials. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials science, engineering, optics, physics, and chemistry into important applications of electronic materials. Sample research topics that span the journal's scope are inorganic, organic, ionic and polymeric materials with properties that include conducting, semiconducting, superconducting, insulating, dielectric, magnetic, optoelectronic, piezoelectric, ferroelectric and thermoelectric. Indexed/Abstracted： Web of Science SCIE Scopus CAS INSPEC Portico