QUALITY OF LIFE IN PREGNANT WOMEN WITH CHRONIC SLOW TRANSIT CONSTIPATION

I. Leschyshyn, L. Markulan, P. Byk, Y. Susak, N. Martyniuk, O. Okhotska
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Abstract

A signifi cant number of pregnant women suff er from constipation, which tends to worsen as pregnancy progresses. Chronicconstipation worsens the course of pregnancy and may require emergency surgery with possible negative consequences for thefetus and the woman. The negative impact of constipation during pregnancy can be reduced by eliminating the manifestation ofsymptoms before it. The recommended surgical procedure is total colectomy. The aim of this study was to evaluate the quality of life (QoL) of pregnant women with chronic slow transit constipation (CSTC) after conservative versus surgical treatment. Method: Between 2017 and 2022, a comprehensive study was conducted on 46 women with CSTC that was resistant to conservative treatment. Among them, 22 patients underwent surgery (group M), while 24 patients received conservative treatment (group C). Quality of life was assessed using the SF-36 scale before treatment, 90 days after treatment initiation, and during each trimester of pregnancy.Rezalts: After treatment, physical QoL was comparable between groups (47.92±3.7 vs. 45.99±4.71), whereas mental QoL was signifi cantly higher in the surgical group (50.59±2.79 vs. 46.94±4.85, p=0.009). In the second trimester, the surgical group had signifi cantly higher physical QoL than the non-surgical group (43.9±2.4 vs. 40.5±2.6, p = 0.029). In the third trimester, both physical (39.3±3.6 vs. 29.7±5.1, p = 0.003) and mental (51.7±2.5 vs. 40.5±6.3, p = 0.003) QoL scores were signifi cantly higher in the surgical group.Conclusions: Compared with conservative therapy, colectomy improves the quality of life of pregnant women with CSTC, suggesting that it is a safe and eff ective treatment option before pregnancy.
慢性缓慢便秘孕妇的生活质量
很多孕妇都有便秘的问题,而且随着孕期的延长,便秘的情况会越来越严重。慢性便秘会使妊娠过程恶化,可能需要进行紧急手术,对胎儿和孕妇都可能造成不良后果。消除孕期便秘的症状可以减少孕期便秘的负面影响。推荐的手术方法是全结肠切除术。本研究旨在评估患有慢性慢传输便秘(CSTC)的孕妇在接受保守治疗和手术治疗后的生活质量(QoL)。研究方法在 2017 年至 2022 年期间,对 46 名保守治疗无效的 CSTC 孕妇进行了一项综合研究。其中,22 名患者接受了手术治疗(M 组),24 名患者接受了保守治疗(C 组)。在治疗前、治疗开始后 90 天以及妊娠期的每个三个月中,采用 SF-36 量表对患者的生活质量进行了评估:治疗后,两组的身体生活质量相当(47.92±3.7 vs. 45.99±4.71),而手术组的精神生活质量明显更高(50.59±2.79 vs. 46.94±4.85,P=0.009)。在妊娠后三个月,手术组的身体QoL明显高于非手术组(43.9±2.4 vs. 40.5±2.6,p=0.029)。在第三孕期,手术组的身体(39.3±3.6 vs. 29.7±5.1,p = 0.003)和心理(51.7±2.5 vs. 40.5±6.3,p = 0.003)QoL评分均显著高于非手术组:结论:与保守疗法相比,结肠切除术可提高 CSTC 孕妇的生活质量,这表明结肠切除术是一种安全有效的孕前治疗方案。
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