External-beam neutron therapy: the first domestic medical unit

Вестник Российской академии наук Pub Date : 2024-07-04 DOI:10.31857/s0869587324010098

Yury S. Mardynsky, I. Gulidov, K. B. Gordon, S. N. Кoryakin, А. N. Solovyov, V. Saburov, S. A. Ivanov, А. D. Kaprin, Т. K. Lobzhanidze, N. V. Маrkov, I. М. Zheleznov, D. Yurkov, О. A. Gerasimchuk, А. Y. Presnyakov, V. I. Zverev, V. P. Smirnov

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Abstract

Modern radiotherapy, employing traditional linear accelerators, has nearly reached its apex in terms of efficacy in treating oncological diseases. The challenge before researchers in the field of implementing cutting-edge technologies pertains to the utilization of fundamentally different therapeutic approaches, one of which is remote neutron therapy. Its salient advantages include an increased relative biological effectiveness of radiation, while the complexities of implementing specific technological solutions encompass forming a beam of the required geometry and spectral characteristics. The article delineates the key milestones in the development of the usage of fast neutron beams for remote radiotherapy, a general description of the neutron therapy complex and its primary structural components is also presented. These are currently being developed as an innovative, mass-producible medical project.

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体外束中子疗法：国内首台医疗设备

采用传统直线加速器的现代放射疗法在治疗肿瘤疾病方面的疗效几乎达到了顶峰。研究人员在实施尖端技术领域面临的挑战与利用根本不同的治疗方法有关，远程中子疗法就是其中之一。远程中子疗法的突出优势包括提高辐射的相对生物有效性，而实施特定技术解决方案的复杂性则包括形成所需的几何形状和光谱特征的光束。文章描述了利用快中子束进行远程放射治疗的重要里程碑，还介绍了中子治疗综合装置及其主要结构组件的总体情况。这些部件目前正在作为一个创新的、可大规模生产的医疗项目进行开发。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Вестник Российской академии наук

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