Nanomedicine in Alzheimer’s Therapy: Enhancing Drug Delivery Strategies

Abstract

Alzheimer's disease (AD), a progressive neurodegenerative disorder, arises from the buildup of beta-amyloid plaques within the intricate neural networks of the brain. A lasting remedy for Alzheimer's disease remains elusive, as current pharmaceutical options merely offer the potential to decelerate its advancement. Nevertheless, nanotechnology has demonstrated its efficacy in the realm of medical interventions. Nanotechnology holds immense promise for the treatment of Alzheimer's disease, particularly in the realms of disease detection and providing alternative therapeutic approaches. With its demonstrated superiority in medical applications, nanotechnology emerges as a potent tool with significant potential in addressing the complexities of Alzheimer's disease, offering enhanced diagnostics and novel treatment strategies. This feat is achieved by augmenting the efficacy of drug administration through the penetration and surmounting of the BBB. Nonetheless, it is crucial to thoroughly investigate and explore the limitations at hand, aiming to minimize undesired side effects and potential toxicity while enhancing medication absorption, thereby optimizing the overall therapeutic outcome. Cutting-edge breakthroughs in Alzheimer's disease treatment utilizing nanotechnology encompass a spectrum of remarkable advancements, including stem cell regeneration, nanomedicine, and neuroprotection. The present investigation delves into the remarkable strides made in nanotechnology, specifically examining its pivotal role in detecting and treating neurodegenerative disorders such as Alzheimer's while shedding light on the challenges ahead.