Nanotechnology Based Therapeutic Approach in Alzheimer's

Md. Samiullah, Kajal Chauhan, Dr. K. Manimekalai, S. H. Sherief, Maulik K. Pandya, Soaib Ahmed, Roushan Bhaskar, Jay Prakash
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Abstract

Alzheimer's disease is a neurodegenerative disorder that ultimately results from the accumulation of beta-amyloid plaques in the brain. The Alzheimer's disease cannot be prevented or cured at this time, and there is no recognised alternative. The medicinal solutions that are currently available can merely slow down its development. However, nanotechnology has demonstrated its applications in the medical field, and it demonstrates a great deal of promise in the treatment of Alzheimer's disease. In particular, it has shown significant promise in the detection of the condition and the development of an alternative technique to cure it. It is necessary for the medication delivery system to have the capability of penetrating and crossing the blood-brain barrier in order to accomplish this need. On the other hand, greater research is necessary in order to discover and overcome these limitations, which have the potential to improve drug absorption while simultaneously reducing toxicity and adverse effects. Certain nanotechnology-based techniques to treating Alzheimer's disease include regenerative medicine, neuroprotection, and stem cell regeneration. These are just few of the emerging approaches. This article's goal is to take a look at nanotechnology from every angle, including its advantages and disadvantages and how it's helping with neurodegenerative disease research and therapy.
基于纳米技术的阿尔茨海默氏症治疗方法
阿尔茨海默病是一种神经退行性疾病,最终是由于大脑中β-淀粉样蛋白斑块的累积造成的。阿尔茨海默病目前无法预防或治愈,也没有公认的替代疗法。现有的药物解决方案只能延缓其发展。然而,纳米技术在医疗领域的应用已经得到证明,它在治疗阿尔茨海默氏症方面大有可为。特别是,它在检测病情和开发替代治疗技术方面大有可为。为了满足这一需求,给药系统必须具备穿透和穿越血脑屏障的能力。另一方面,有必要开展更多研究,以发现并克服这些限制,从而有可能在改善药物吸收的同时降低毒性和不良反应。治疗阿尔茨海默病的某些纳米技术包括再生医学、神经保护和干细胞再生。这些只是新兴方法中的一小部分。本文旨在从各个角度介绍纳米技术,包括其优缺点以及如何帮助神经退行性疾病的研究和治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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