{"title":"BEHAVIOR OF BLADDER AFTER TURP IN UNDERACTIVE DETRUSOR PATIENTS","authors":"Pranab Patnaik, Vikalap Gupta, S. Das","doi":"10.22159/ajpcr.2024v17i7.51316","DOIUrl":null,"url":null,"abstract":"Objective: The gold standard therapy for benign prostatic obstruction is transurethral resection of the prostate (TURP). Because it improves outlet resistance, it may also be useful for individuals who have detrusor underactivity (DU) with lower urinary tract dysfunction that is refractory to medicinal therapy or in situations with a substantial residual urine volume. The objective of the current study was to assess the urodynamic behavior of the bladder following TURP in DU patients.\nMethods: This research examined and analyzed 41 individuals with DU (mean age 68.7 years). All these patients had a TURP for a suspected outlet blockage. All these patients had extensive pre-operative evaluations and urodynamics assessments before and after TURP. We compared maximum flow rate (Qmax), international prostate symptom score (IPSS), post-void residuals (PVR), quality of life (QoL) along with other urodynamic parameters assessing detrusor function like bladder contractility index (BCI), and detrusor pressure at Qmax (pdetQmax) pre- and post-TURP.\nResults: The average duration of follow-up of patients was 9.2 months. Following TURP, the mean IPSS and QoL improvement was statistically significant. Following TURP, there was also a substantial decrease in PVR while we observed an improvement in Qmax value. Even after TURP, there was no substantial change in total cystometric capacity, BCI, or pdetQmax index.\nConclusion: DU may not be an absolute contraindication to TURP. Despite the presence of DU, the prognosis of TURP may be optimistic if the patients have evident bladder outlet obstruction. However, medically removing the blockage does not increase contractility, which is essential when evaluating and advising on TURP surgery.","PeriodicalId":8528,"journal":{"name":"Asian Journal of Pharmaceutical and Clinical Research","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asian Journal of Pharmaceutical and Clinical Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22159/ajpcr.2024v17i7.51316","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: The gold standard therapy for benign prostatic obstruction is transurethral resection of the prostate (TURP). Because it improves outlet resistance, it may also be useful for individuals who have detrusor underactivity (DU) with lower urinary tract dysfunction that is refractory to medicinal therapy or in situations with a substantial residual urine volume. The objective of the current study was to assess the urodynamic behavior of the bladder following TURP in DU patients.
Methods: This research examined and analyzed 41 individuals with DU (mean age 68.7 years). All these patients had a TURP for a suspected outlet blockage. All these patients had extensive pre-operative evaluations and urodynamics assessments before and after TURP. We compared maximum flow rate (Qmax), international prostate symptom score (IPSS), post-void residuals (PVR), quality of life (QoL) along with other urodynamic parameters assessing detrusor function like bladder contractility index (BCI), and detrusor pressure at Qmax (pdetQmax) pre- and post-TURP.
Results: The average duration of follow-up of patients was 9.2 months. Following TURP, the mean IPSS and QoL improvement was statistically significant. Following TURP, there was also a substantial decrease in PVR while we observed an improvement in Qmax value. Even after TURP, there was no substantial change in total cystometric capacity, BCI, or pdetQmax index.
Conclusion: DU may not be an absolute contraindication to TURP. Despite the presence of DU, the prognosis of TURP may be optimistic if the patients have evident bladder outlet obstruction. However, medically removing the blockage does not increase contractility, which is essential when evaluating and advising on TURP surgery.