A Review on Environment-friendly Protocol for the Synthesis of Pyrazole Derivative

Abstract

Pyrazole derivatives are a significant group of heterocyclic compounds that have a diverse variety of biological activities and are used in several fields, such as medicines, agrochemicals, and materials research. Conventional methods for synthesizing pyrazole derivatives typically require severe reaction conditions, hazardous reagents, and environmentally harmful solvents, presenting considerable obstacles to achieving sustainable chemistry. This analysis specifically examines the latest progress made in creating environmentally friendly procedures for producing pyrazole derivatives. The study investigates different strategies in green chemistry, such as reactions without solvents, techniques including microwave and ultrasonic assistance, and using renewable resources and environmentally friendly catalysts. An in-depth analysis is conducted to evaluate the efficiency, selectivity, and environmental impact of these approaches. This review intends to comprehensively explore the potential for sustainable practices in synthesizing pyrazole derivatives by emphasizing advancements in green synthetic methods. It seeks to encourage further research and use of green chemistry concepts in heterocyclic chemistry.