Effectiveness of Nimbasava Nasya with Sigru Beeja in Acute Exacerbation of Chronic Rhino Sinusitis - A Comparative Clinical Trial

IF 0.1 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
Neethu Kesavan, Thrijil Krishnan EM, Sreeja Sukesan
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Abstract

Chronic Rhinosinusitis is defined as a group of disorders characterized by inflammation of the mucosa of the nose and paranasal sinuses lasting for more than 12 weeks.  Acute exacerbation of Chronic Rhinosinusitis is defined as a sudden worsening of symptoms in a patient who has chronic sinusitis. According to the science of Ayurveda, Dushta Pratisyaya condition, is in proximity to chronic sinusitis. Asava (fermented formulation) is mentioned for Virechana Nasya (type of Errhine therapy).  Nimbasava is a formulation of Asava Kalpana prepared with Guggulu Tikthaka Gritha Yoga explained in Vaatavyadhi Chikitsa. Sigrubeeja (seed of Moringa Oleifera) and Saindhava (rock salt) are explained among Shirovirechana Gana (a group of medicines that can be used for nasal administration). The study was conducted on 30 patients of chronic sinusitis who were randomly divided into two groups and were given treatment for 7 days and follow-up after for 3 months. Out of two groups, 15 patients were given Virechana Nasya with Nimbasava, Sigru Beeja, and Saindhava for 7 days. The other 15 patients were treated as a standard control group and given the modern conventional management with Amoxicillin Clavulanate 500 mg, Fluticasone nasal spray, and Otrivin nasal drops for 7 days. The statistical analysis of data was done with the Wilcoxon Signed Rank Test and Mann-Whitney U test. During this trial, it was observed that Nimbasava Nasya with Sigrubeeja is effective in acute exacerbation of Chronic Rhinosinusitis. Pain relieving action of this Nasya was statistically highly significant. It was also found that the effectiveness of Nasya is more in reducing the recurrence of acute exacerbations of Chronic Rhinosinusitis.
Nimbasava Nasya 与 Sigru Beeja 对慢性犀牛鼻窦炎急性加重期的疗效对比临床试验
慢性鼻窦炎是指一组以鼻腔和副鼻窦粘膜炎症为特征的疾病,持续时间超过 12 周。 慢性鼻窦炎急性加重是指慢性鼻窦炎患者的症状突然恶化。根据阿育吠陀科学,Dushta Pratisyaya 病症接近慢性鼻窦炎。Asava (发酵配方)被用于 Virechana Nasya(Erhine 治疗的一种)。 Nimbasava 是 Asava Kalpana 与 Guggulu Tikthaka Gritha Yoga 配制而成的配方,在 Vaatavyadhi Chikitsa 中有所解释。Sigrubeeja(辣木种子)和 Saindhava(岩盐)属于 Shirovirechana Gana(一组可用于鼻腔给药的药物)。这项研究对 30 名慢性鼻窦炎患者进行了调查,他们被随机分为两组,分别接受 7 天的治疗和 3 个月的随访。在两组患者中,15 名患者接受了为期 7 天的含有 Nimbasava、Sigru Beeja 和 Saindhava 的 Virechana Nasya 治疗。另外 15 名患者作为标准对照组,接受为期 7 天的现代常规治疗,使用阿莫西林克拉维酸钾 500 毫克、氟替卡松鼻腔喷雾剂和奥曲肽滴鼻剂。数据统计分析采用 Wilcoxon Signed Rank 检验和 Mann-Whitney U 检验。试验结果表明,Nimbasava Nasya 和 Sigrubeeja 对慢性鼻炎的急性加重有效。该 Nasya 的止痛作用在统计学上非常显著。研究还发现,Nimbasava Nasya 在减少慢性鼻炎急性加重期复发方面的效果更好。
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来源期刊
International Journal of Ayurvedic Medicine
International Journal of Ayurvedic Medicine MEDICINE, RESEARCH & EXPERIMENTAL-
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50.00%
发文量
87
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