Physiochemical and phytochemical analysis of Karanthai legium - Siddha herbomineral formulation

Abstract

Siddha system of medicine is one of the holistic systems. The consumption of traditional medicine is also in upward trend. To manufacture any herbal drug the quality and safety of the drug is to be estimated. Karanthai legium (KL) is one of the herbomineral formulation indicated for kiranthi (Skin disease), karappan (Eczema), soolai (Pain), yoni putru (Cervical cancer), kunmam (Ulcer). This study aims to develop standardization of Karanthai legium as per PLIM (Pharmacopeia Laboratory of Indian Medicine) guidelines. The test drug KL focused on Physico-chemical analysis, Phytochemical Analysis, Oraganoleptic character, Instrumental analysis such as heavy metal analysis, HPTLC Analysis, Aflatoxin, Pesticide residue, Specific pathogen and Microbial contamination. Physiochemical analysis report showed loss of drying KL is 14.96%, total ash is 0.92%, acid insoluble ash is 0.17%, water soluble ash is 0.50%,pH of KL is 5.45.The drug KL had HPTLC fingerprint analysis revealed the presence of nine phytocomponents at 254nm, eight phytocomponents at 366nm and six phytocomponents at 520nm.The heavy metal analysis showed no trace of heavy metal residue in KL. This study revealed the data regarding the physicochemical characterisation of Karanthai legium, which will be helpful in standardising the drugs and for further comparison studies.