Factors Determining Quality of Drug Information by Hospital Pharmacies—Results from Five-Year Annual Quality Assessment

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS

ACS Applied Bio Materials Pub Date : 2024-07-13 DOI:10.3390/pharmacy12040109

D. Strobach, Ute Chiriac, Sigrun Klausner, Sabine Krebs, Claudia Langebrake, Christiane Querbach, Carolin Schuhmacher, Rickmer Schulte, Simon Wiegrebe, Ute Amann

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引用次数: 0

Abstract

Drug information (DI) provided by hospital pharmacies aims to promote rational and safe drug therapy. While quality assessment for this task is recommended, more knowledge on the factors determining the quality is needed. We aimed to evaluate the impacts of different factors on the quality of DI provided by hospital pharmacies to healthcare professionals. Retrospectively, answers on fictitious enquiries about annual DI tests for German hospital pharmacies over five years were evaluated for content-related and structural requirements. Multivariate analysis was performed for the impact of the enquiry complexity, DI organization (specialized DI center; pharmacist responsible per day; DI on top of other routine tasks), and quality measures (second look; experience of answering pharmacist in DI/on ward; use of documentation database). In 2017–2021, 45, 71, 79, 118, and 122 hospital pharmacies participated. The enquiry complexity had a statistically significant impact on the content-related quality, with poor results for a higher complexity (years 2018/2021, OR 0.25/0.04, p < 0.01). The DI centers achieved better results regarding content-related quality than for a pharmacist responsible per day (OR 0.76/p = 0.65) or DI on top of routine tasks (OR 0.35/p = 0.02). The DI centers scored better in structural quality. The second look showed an overall trend of a better content-related and structural quality. In conclusion, specialized DI centers and second looks are recommended as quality-improving measures. Training for answering complex enquiries should be intensified.

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决定医院药房药品信息质量的因素--五年期年度质量评估结果

医院药房提供的药物信息（DI）旨在促进合理、安全的药物治疗。虽然我们建议对这项工作进行质量评估，但还需要对决定质量的因素有更多了解。我们的目的是评估不同因素对医院药房向医护人员提供的药品信息质量的影响。我们回顾性地评估了德国医院药房五年来对年度 DI 测试的虚假查询答复，以确定其内容相关性和结构要求。对询问复杂性、DI 组织（专门的 DI 中心；药剂师每天负责；DI 在其他常规任务之外）和质量措施（二次观察；回答问题的药剂师在 DI/病房的经验；文件数据库的使用）的影响进行了多变量分析。2017-2021 年，分别有 45、71、79、118 和 122 家医院药房参与。查询复杂程度对内容相关质量有显著的统计学影响，复杂程度越高，结果越差（2018/2021 年，OR 0.25/0.04，P < 0.01）。与每天负责的药剂师（OR 0.76/p = 0.65）或日常任务之外的 DI（OR 0.35/p = 0.02）相比，DI 中心在内容相关质量方面取得了更好的结果。DI 中心的结构质量得分更高。第二次调查显示，与内容相关的质量和结构质量总体上呈上升趋势。总之，建议将专门的 DI 中心和二次查询作为提高质量的措施。应加强回答复杂查询的培训。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Applied Bio Materials Chemistry-Chemistry (all)

CiteScore

9.40

自引率

2.10%

发文量

464

期刊介绍： ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.