Surgical outcomes of external double needle puncture epiglottopexy in severe laryngomalacia patients with high-risk comorbidities

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Subi Oh, Younghac Kim, Hyo Jun Kim, Man Ki Chung, Han-Sin Jeong, Young-Ik Son, Nayeon Choi
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Abstract

Objectives

Patients with severe laryngomalacia (LM) and high-risk comorbidities require surgical interventions such as supraglottoplasty. However, evidence supporting epiglottopexy for these patients is scarce. This study aims to report the surgical outcomes of external double needle puncture using a single thread for epiglottopexy in severe LM patients with high-risk comorbidities.

Methods

This retrospective study was conducted at a single tertiary hospital. We enrolled 32 patients under 12 months with severe LM who underwent external double needle puncture epiglottopexy. We compared clinical factors between the successful and failed groups and identified risk factors for the failure of epiglottopexy.

Results

Of the airway surgical outcomes, 22 (68.7 %) patients were in the successful group. In the failed group (n = 10, 32.3 %), patients received tracheostomies due to uncontrolled saliva (n = 3), the need for mechanical ventilation (n = 3), and uncontrolled LM (n = 4). There was a statistically significant difference in body weight at the time of surgery and the proportion of associated comorbidities between the two groups. Gestational age was the only factor significantly associated with successful surgical outcomes in both univariate and multivariate logistic regression analyses (odds ratio = 2.263; 95 % confidence interval, 1.042–4.918; P = 0.039).

Conclusion

External double needle puncture epiglottopexy is an effective surgical method for patients with LM who present with a retroflexed floppy epiglottis and high-risk comorbidities. Low gestational age is a major risk factor for surgical failure. Consideration of factors such as the need for mechanical ventilation and uncontrolled saliva should be prioritized before and after surgery to enhance surgical success.

对患有高风险合并症的重度喉头水肿患者进行外双针穿刺会厌成形术的手术效果
目的严重喉缺损(LM)和高危合并症患者需要进行声门上成形术等手术干预。然而,支持对这些患者进行会厌成形术的证据却很少。本研究旨在报告对患有高风险合并症的重度 LM 患者使用单线外双针穿刺进行会厌成形术的手术效果。我们招募了 32 名 12 个月以下的重度 LM 患者,他们都接受了体外双针穿刺会厌成形术。我们比较了成功组和失败组的临床因素,并确定了会厌成形术失败的风险因素。在失败组(10 人,32.3%)中,患者因唾液失控(3 人)、需要机械通气(3 人)和 LM失控(4 人)而接受气管造口术。两组患者手术时的体重和相关合并症的比例存在显著统计学差异。在单变量和多变量逻辑回归分析中,妊娠年龄是唯一与手术成功率显著相关的因素(几率比 = 2.263;95 % 置信区间,1.042-4.918;P = 0.039)。低妊娠年龄是手术失败的主要风险因素。手术前后应优先考虑需要机械通气和唾液失控等因素,以提高手术成功率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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