Clinical characteristics and outcomes of COVID-19 cases admitted to adult intensive care units during the pandemic: A single center experience

IF 4.7 3区 医学 Q1 INFECTIOUS DISEASES
Majid M. Alshamrani , Aiman El-Saed , Abdulrahman Alalmai , Mohammed Abdulrahman Almanna , Saad Mohammed Dhafer Alqahtani , Mohammed Saad Asiri , Sulaiman Saleh Almasoud , Fatmah Othman
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引用次数: 0

Abstract

Background

COVID-19 is the largest recorded pandemic in history. It causes several complications such as shock, pneumonia, acute respiratory distress syndrome, and organ failure. The objective was to determine COVID-19 outcomes and risk factors in the intensive care (ICU) setting.

Methods

A retrospective review of prospectively collected data was conducted. Adult patients with a positive RT-PCR test for COVID-19 admitted to ICUs of a tertiary care hospital between 2020 and 2022 were included. Patients who had severe complex trauma were excluded. The outcomes examined included ventilation use and duration, length of stay (LOS), and mortality.

Results

A total of 964 patients were included. The mean ( ± standard deviation, SD) age was 63.7 ± 16.9 years. The majority of the patients were males (59.0 %) and Saudi (75.7 %). Ventilation use was documented in 443 (57.1 %) patients, with a mean ( ± SD) ventilation duration of 9.7 ± 8.4 days. Death occurred in 361 (37.4 %) patients after a mean ( ± SD) of 33.3 ± 44.5 days from infection. The mean ( ± SD) LOS was 30.6 ± 54.1 days in hospital and 5.2 ± 5.4 days in ICU. Ventilation use was associated with older age, males, longer ICU LOS, mortality, and admission to medical-surgical ICU. Crude mortality use was associated with older age, longer ICU LOS, use of ventilator, shorter ventilation duration, and admission to medical-surgical or respiratory ICUs.

Conclusions

COVID-19 patients admitted to adult ICUs are at high risk of death and mechanical ventilation. The crude risks of both outcomes are higher in older age and longer ICU LOS and are very variable by ICU type.

大流行期间入住成人重症监护病房的 COVID-19 病例的临床特征和预后:单一中心的经验
背景COVID-19 是有史以来记录在案的最大流行病。它可引起多种并发症,如休克、肺炎、急性呼吸窘迫综合征和器官衰竭。研究旨在确定重症监护病房(ICU)中 COVID-19 的结果和风险因素。纳入了 2020 年至 2022 年期间入住一家三级医院重症监护病房、COVID-19 RT-PCR 检测呈阳性的成人患者。排除了严重复杂创伤患者。研究结果包括通气使用和持续时间、住院时间(LOS)和死亡率。平均年龄(± 标准差,SD)为 63.7±16.9 岁。大多数患者为男性(59.0%)和沙特人(75.7%)。根据记录,443 名患者(57.1%)使用了通气治疗,平均(± 标准差)通气时间为 9.7 ± 8.4 天。361名患者(37.4%)在感染后平均(± SD)33.3±44.5天后死亡。平均(± SD)住院时间为 30.6 ± 54.1 天,重症监护室为 5.2 ± 5.4 天。使用通气与年龄较大、男性、ICU LOS 较长、死亡率和入住内外科 ICU 有关。粗死亡率与年龄较大、ICU LOS 较长、使用呼吸机、通气时间较短、入住内外科或呼吸科 ICU 有关。年龄越大、重症监护室持续时间越长的患者出现这两种结果的粗风险越高,而且不同重症监护室类型的粗风险差异很大。
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来源期刊
Journal of Infection and Public Health
Journal of Infection and Public Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH -INFECTIOUS DISEASES
CiteScore
13.10
自引率
1.50%
发文量
203
审稿时长
96 days
期刊介绍: The Journal of Infection and Public Health, first official journal of the Saudi Arabian Ministry of National Guard Health Affairs, King Saud Bin Abdulaziz University for Health Sciences and the Saudi Association for Public Health, aims to be the foremost scientific, peer-reviewed journal encompassing infection prevention and control, microbiology, infectious diseases, public health and the application of healthcare epidemiology to the evaluation of health outcomes. The point of view of the journal is that infection and public health are closely intertwined and that advances in one area will have positive consequences on the other. The journal will be useful to all health professionals who are partners in the management of patients with communicable diseases, keeping them up to date. The journal is proud to have an international and diverse editorial board that will assist and facilitate the publication of articles that reflect a global view on infection control and public health, as well as emphasizing our focus on supporting the needs of public health practitioners. It is our aim to improve healthcare by reducing risk of infection and related adverse outcomes by critical review, selection, and dissemination of new and relevant information in the field of infection control, public health and infectious diseases in all healthcare settings and the community.
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