Effect of fixed-ratio insulin combinations on adherence in type 2 diabetes: Systematic review

IF 4.3 Q1 ENDOCRINOLOGY & METABOLISM

Diabetes & Metabolic Syndrome-Clinical Research & Reviews Pub Date : 2024-06-01 DOI:10.1016/j.dsx.2024.103072

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引用次数: 0

Abstract

Aims

To systematically review evidence on the effect of fixed-ratio combinations on adherence in people with type 2 diabetes.

Methods

Systematic searches were conducted using MEDLINE and EMBASE in March 2023. Standardised screening, data extraction and risk of bias assessment were conducted. All review procedures were conducted independently by two reviewers. Eligible studies assessed the effect of fixed-ratio combinations on adherence in people with type 2 diabetes. Narrative synthesis was conducted to analyse findings.

Results

A total of 488 records were identified, of which 37 proceeded to full-text screening and 7 – each representing a unique study – were included in the systematic review. Among the included studies, 3 were randomised controlled trials and 4 were cohort studies. Following narrative synthesis, it was shown that fixed-ratio combinations improved patient satisfaction and treatment adherence.

Conclusions

Available evidence supports a benefit for fixed-ratio combinations on patient satisfaction and treatment adherence in people with type 2 diabetes.

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固定比例胰岛素组合对 2 型糖尿病患者坚持用药的影响：系统回顾

目的对固定比值组合对 2 型糖尿病患者依从性的影响的证据进行系统综述。方法在 2023 年 3 月使用 MEDLINE 和 EMBASE 进行系统检索。进行了标准化筛选、数据提取和偏倚风险评估。所有审查程序均由两名审查员独立完成。符合条件的研究评估了固定比例组合对 2 型糖尿病患者依从性的影响。结果共发现 488 条记录，其中 37 条进入全文筛选，7 条（每条代表一项独特的研究）被纳入系统综述。在纳入的研究中，3 项为随机对照试验，4 项为队列研究。结论现有证据表明，固定比例组合可提高 2 型糖尿病患者的满意度和治疗依从性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diabetes & Metabolic Syndrome-Clinical Research & Reviews ENDOCRINOLOGY & METABOLISM-

CiteScore

22.90

自引率

2.00%

发文量

248

审稿时长

51 days

期刊介绍： Diabetes and Metabolic Syndrome: Clinical Research and Reviews is the official journal of DiabetesIndia. It aims to provide a global platform for healthcare professionals, diabetes educators, and other stakeholders to submit their research on diabetes care. Types of Publications: Diabetes and Metabolic Syndrome: Clinical Research and Reviews publishes peer-reviewed original articles, reviews, short communications, case reports, letters to the Editor, and expert comments. Reviews and mini-reviews are particularly welcomed for areas within endocrinology undergoing rapid changes.