Does the extent of bone defects affect the time to reach full weight-bearing after treatment with the Masquelet technique?

Q3 Biochemistry, Genetics and Molecular Biology
J. Frese , AP Schulz , B. Kowald , U.J. Gerlach , K.H. Frosch , R. Schoop
{"title":"Does the extent of bone defects affect the time to reach full weight-bearing after treatment with the Masquelet technique?","authors":"J. Frese ,&nbsp;AP Schulz ,&nbsp;B. Kowald ,&nbsp;U.J. Gerlach ,&nbsp;K.H. Frosch ,&nbsp;R. Schoop","doi":"10.1016/j.bbiosy.2024.100098","DOIUrl":null,"url":null,"abstract":"<div><h3>Methodology</h3><p>In a consecutive retrospective analysis of 190 patients treated with the Masquelet technique at the BG Klinikum Hamburg from January 2012 to January 2022, subgroup analysis for defect-specific features such as the extent and morphology of the defect were recorded, and their influence on the time to reach full weight-bearing of the affected limb was investigated.</p></div><div><h3>Results and conclusion</h3><p>A total of 217 defects were treated in 190 patients using the Masquelet technique. 70 % of all defects were in the tibia, followed by 22 % in the femur and only about 7 % in the upper extremity. The average length of all defects was 58 mm (+/- 31 mm), with the largest defect measuring 180 mm and the smallest measuring 20 mm. 89 % of the patients achieved full weight-bearing at the end of therapy. The average time from initiation of therapy to reaching safe full weight-bearing was 589 days. There was a significant correlation between defect length and time to reach full weight-bearing (<em>p</em> = 0.0134). These results could serve as a basis for creating a score for prognostics and evaluation of bone healing after treatment with the Masquelet technique. Additionally, the results could help guide indications for secondary stabilization using internal fixation.</p></div>","PeriodicalId":72379,"journal":{"name":"Biomaterials and biosystems","volume":"15 ","pages":"Article 100098"},"PeriodicalIF":0.0000,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666534424000114/pdfft?md5=f1a313bc2ac6cefc2dc820cd03006840&pid=1-s2.0-S2666534424000114-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomaterials and biosystems","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666534424000114","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Biochemistry, Genetics and Molecular Biology","Score":null,"Total":0}
引用次数: 0

Abstract

Methodology

In a consecutive retrospective analysis of 190 patients treated with the Masquelet technique at the BG Klinikum Hamburg from January 2012 to January 2022, subgroup analysis for defect-specific features such as the extent and morphology of the defect were recorded, and their influence on the time to reach full weight-bearing of the affected limb was investigated.

Results and conclusion

A total of 217 defects were treated in 190 patients using the Masquelet technique. 70 % of all defects were in the tibia, followed by 22 % in the femur and only about 7 % in the upper extremity. The average length of all defects was 58 mm (+/- 31 mm), with the largest defect measuring 180 mm and the smallest measuring 20 mm. 89 % of the patients achieved full weight-bearing at the end of therapy. The average time from initiation of therapy to reaching safe full weight-bearing was 589 days. There was a significant correlation between defect length and time to reach full weight-bearing (p = 0.0134). These results could serve as a basis for creating a score for prognostics and evaluation of bone healing after treatment with the Masquelet technique. Additionally, the results could help guide indications for secondary stabilization using internal fixation.

骨缺损程度是否会影响马斯奎莱技术治疗后达到完全负重的时间?
方法对 2012 年 1 月至 2022 年 1 月期间在汉堡 BG Klinikum 采用 Masquelet 技术治疗的 190 名患者进行连续回顾性分析,记录缺陷的范围和形态等缺陷特异性特征的亚组分析,并研究其对患肢完全负重时间的影响。胫骨缺损占所有缺损的 70%,股骨缺损占 22%,上肢缺损仅占 7%。所有缺损的平均长度为 58 毫米(+/- 31 毫米),最大缺损为 180 毫米,最小缺损为 20 毫米。89%的患者在治疗结束后实现了完全负重。从开始治疗到安全完全负重的平均时间为 589 天。缺损长度与达到完全负重的时间之间存在明显的相关性(p = 0.0134)。这些结果可以作为马斯奎莱技术治疗后建立预后和骨愈合评估评分的基础。此外,这些结果还有助于指导使用内固定进行二次稳定的适应症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
4.10
自引率
0.00%
发文量
0
审稿时长
25 days
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信