Oxylipin Dynamics Following A Single Bout of Yoga Exercise: A Pilot Randomized Controlled Trial Secondary Analysis.

IF 1.3 4区医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE

Journal of Integrative and Complementary Medicine Pub Date : 2024-09-01 Epub Date: 2024-07-15 DOI:10.1089/jicm.2024.0233

Dennis Muñoz-Vergara, Pamela M Rist, EunMee Yang, Gloria Y Yeh, Norman Lee, Peter M Wayne

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Abstract

Background: Yoga may promote health via a complex modulation of inflammation. Little is known about oxylipins, a class of circulating mediators involved in inflammation resolution. Objective: To explore the acute effects of yoga exercise on systemic levels of oxylipins. Methods: This is a secondary analysis of a three-arm (high-intensity-yoga: HY, n = 10); moderate-intensity-yoga: MY, n = 10; and no-intervention-control: CON, n = 10) pilot randomized controlled trial employing a single bout of yoga exercise. Blood samples (baseline and 4-timepoint post-intervention) were used for an unbiased metabolipidomic profiling analysis. Net Areas Under the Curve per oxylipin were evaluated for each group. Results: Lipoxin(LX)B4, prostaglandin(PG)D2, and resolvin(Rv)D3 exhibited a greater magnitude of change in HY compared with MY and CON. Conclusion: Findings inform the design of future trials exploring the acute effects of yoga exercise on oxylipins' systemic levels.

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单次瑜伽运动后的血脂动态：试验性随机对照试验二次分析。

背景：瑜伽可通过复杂的炎症调节促进健康。人们对参与消炎的一类循环介质--氧脂素知之甚少。目的：探讨瑜伽运动对氧化脂蛋白的急性影响：探索瑜伽运动对全身氧化脂蛋白水平的急性影响。方法这是对一项三臂研究（高强度瑜伽：HY，n = 10）、中等强度瑜伽：MY，n = 10 和无强度瑜伽：MY，n = 10）的二次分析：MY，n = 10；无干预对照组：CON，n = 10）试验性随机对照试验，采用单次瑜伽锻炼。血液样本（基线和干预后 4 个时间点）用于无偏见的代谢脂质体分析。评估了每组每个氧脂素的曲线下净面积。结果与 MY 和 CON 相比，HY 组的脂氧素（LX）B4、前列腺素（PG）D2 和溶血素（Rv）D3 的变化幅度更大。结论研究结果为今后探讨瑜伽运动对全身氧化脂素水平的急性影响的试验设计提供了参考。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Integrative and Complementary Medicine

CiteScore

4.30

自引率

0.00%

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