Osteogenesis imperfecta type II with patent ductus arteriosus, severe persistent pulmonary hypertension, sepsis and severe thrombocytopenia in a neonate: A case report

Global pediatrics Pub Date : 2024-07-05 DOI:10.1016/j.gpeds.2024.100203

Mansoor Aslamzai , Mohammad Sharif Sediqi , Mohmand Mangal , Ataullah Shinwarie

{"title":"Osteogenesis imperfecta type II with patent ductus arteriosus, severe persistent pulmonary hypertension, sepsis and severe thrombocytopenia in a neonate: A case report","authors":"Mansoor Aslamzai , Mohammad Sharif Sediqi , Mohmand Mangal , Ataullah Shinwarie","doi":"10.1016/j.gpeds.2024.100203","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Osteogenesis imperfecta type II is a rare congenital anomaly that usually causes death in utero or shortly after birth.</p></div><div><h3>Case Presentation</h3><p>This study reports a rare case of osteogenesis imperfecta type II in an Afghan girl who was one day old. The defect was accompanied by a patent ductus arteriosus, severe persistent pulmonary hypertension of the newborn, sepsis, severe thrombocytopenia, and low birth weight during the first four days of life. These disorders were diagnosed by medical history, physical examination, blood investigation, computed tomography, x-ray, and doppler ultrasonography. On the fifth day of life, the newborn suffered an abrupt cardio-pulmonary arrest that resulted in her death, presumably due to brainstem compression or severe persistent pulmonary hypertension of the newborn.</p></div><div><h3>Conclusion</h3><p>Osteogenesis imperfecta type II can result in life-threatening complications during the first week of life.</p></div>","PeriodicalId":73173,"journal":{"name":"Global pediatrics","volume":"9 ","pages":"Article 100203"},"PeriodicalIF":0.0000,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266700972400071X/pdfft?md5=8440e903f407a366a14cb6ed93fb7f65&pid=1-s2.0-S266700972400071X-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Global pediatrics","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S266700972400071X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Osteogenesis imperfecta type II is a rare congenital anomaly that usually causes death in utero or shortly after birth.

Case Presentation

This study reports a rare case of osteogenesis imperfecta type II in an Afghan girl who was one day old. The defect was accompanied by a patent ductus arteriosus, severe persistent pulmonary hypertension of the newborn, sepsis, severe thrombocytopenia, and low birth weight during the first four days of life. These disorders were diagnosed by medical history, physical examination, blood investigation, computed tomography, x-ray, and doppler ultrasonography. On the fifth day of life, the newborn suffered an abrupt cardio-pulmonary arrest that resulted in her death, presumably due to brainstem compression or severe persistent pulmonary hypertension of the newborn.

Conclusion

Osteogenesis imperfecta type II can result in life-threatening complications during the first week of life.

查看原文本刊更多论文

新生儿 II 型成骨不全伴动脉导管未闭、严重持续性肺动脉高压、败血症和严重血小板减少症：病例报告

背景II型成骨不全症是一种罕见的先天性畸形，通常会导致婴儿在子宫内或出生后不久死亡。本研究报告了一例罕见的II型成骨不全症病例，患儿是一名出生仅一天的阿富汗女童。该缺陷伴有动脉导管未闭、新生儿严重的持续性肺动脉高压、败血症、严重血小板减少症，以及出生后头四天体重过轻。这些疾病都是通过病史、体格检查、血液检查、计算机断层扫描、X 光检查和多普勒超声波检查确诊的。新生儿在出生后第五天突然心肺功能骤停导致死亡，可能是由于脑干受压或新生儿严重的持续性肺动脉高压所致。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Global pediatrics Perinatology, Pediatrics and Child Health

自引率

0.00%

发文量