Risk factors associated with radiological and clinical recurrences after laparoscopic repair of large hiatal hernia with TiO2Mesh™ reinforcement.

IF 2.6 2区 医学 Q1 SURGERY
Hernia Pub Date : 2024-10-01 Epub Date: 2024-07-13 DOI:10.1007/s10029-024-03107-8
Pablo Priego, Luz Divina Juez, Marta Cuadrado, Juan Carlos García Pérez, Silvia Sánchez-Picot, Luis Alberto Blázquez, Pablo Gil, Julio Galindo, José María Fernández-Cebrián
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引用次数: 0

Abstract

Introduction: Laparoscopic repair of large para-esophageal hiatal hernias (LPHH) remains controversial. Several meta-analyses suggest hiatus reinforcement with mesh has better outcomes over cruroplasty in terms of less recurrence. The aim of this study was to evaluate the medium-term results of treating LPHH with a biosynthetic monofilament polypropylene mesh coated with titanium dioxide to enhance biocompatibility (TiO2Mesh™).

Methods: A retrospective observational study, using data extracted from a prospectively collected database was performed at XXX from December 2014 to June 2023. Included participants were all patients who underwent laparoscopic repair of large (> 5 cm) type III hiatal hernia in which a TiO2Mesh™ was used. The results of the study, including clinical and radiological recurrences as well as mesh-related morbidity, were analyzed.

Results: Sixty-seven patients were finally analyzed. Laparoscopic approach was attempted in all but conversion was needed in one patient because of bleeding in the lesser curvature. With a median follow-up of 41 months (and 10 losses to follow-up), 22% of radiological recurrences and 19.3% of clinical recurrences were described. Regarding complications, one patient presented morbidity associated with the mesh (mesh erosion requiring endoscopic extraction). Recurrent hernia repair was an independent factor of clinical recurrence (OR 4.57 95% CI (1.28-16.31)).

Conclusion: LPHH with TiO2Mesh™ is safe and feasible with a satisfactory medium-term recurrence and a low complication rate. Prospective randomized studies are needed to establish the standard repair of LPHH.

Abstract Image

使用 TiO2Mesh™ 加固技术进行腹腔镜大食道裂孔疝修补术后放射学和临床复发的相关风险因素。
导言:大型食道旁裂孔疝(LPHH)的腹腔镜修复术仍存在争议。多项荟萃分析表明,在减少复发方面,用网片加固食道裂孔的效果优于椎体成形术。本研究旨在评估使用涂有二氧化钛以增强生物相容性的生物合成单丝聚丙烯网片(TiO2Mesh™)治疗 LPHH 的中期效果:从 2014 年 12 月至 2023 年 6 月,XXX 使用从前瞻性收集的数据库中提取的数据进行了一项回顾性观察研究。研究对象包括所有接受腹腔镜修补术的大型(大于 5 厘米)III 型食管裂孔疝患者,修补术中使用了 TiO2Mesh™。研究结果包括临床和放射学复发率以及与网片相关的发病率:结果:最终分析了 67 例患者。所有患者都尝试了腹腔镜手术,但有一名患者因小弯处出血而需要转为腹腔镜手术。中位随访时间为41个月(10例失去随访机会),22%的患者出现放射学复发,19.3%的患者出现临床复发。在并发症方面,一名患者的发病与网片有关(网片侵蚀,需要在内窥镜下取出)。复发疝修补术是临床复发的一个独立因素(OR 4.57 95% CI (1.28-16.31)):使用 TiO2Mesh™ 进行 LPHH 安全可行,中期复发率令人满意,并发症发生率较低。需要进行前瞻性随机研究,以确定 LPHH 的标准修复方法。
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来源期刊
Hernia
Hernia SURGERY-
CiteScore
4.90
自引率
26.10%
发文量
171
审稿时长
4-8 weeks
期刊介绍: Hernia was founded in 1997 by Jean P. Chevrel with the purpose of promoting clinical studies and basic research as they apply to groin hernias and the abdominal wall . Since that time, a true revolution in the field of hernia studies has transformed the field from a ”simple” disease to one that is very specialized. While the majority of surgeries for primary inguinal and abdominal wall hernia are performed in hospitals worldwide, complex situations such as multi recurrences, complications, abdominal wall reconstructions and others are being studied and treated in specialist centers. As a result, major institutions and societies are creating specific parameters and criteria to better address the complexities of hernia surgery. Hernia is a journal written by surgeons who have made abdominal wall surgery their specific field of interest, but we will consider publishing content from any surgeon who wishes to improve the science of this field. The Journal aims to ensure that hernia surgery is safer and easier for surgeons as well as patients, and provides a forum to all surgeons in the exchange of new ideas, results, and important research that is the basis of professional activity.
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