Characteristics of anaphylaxis from tertiary-care hospital in lower northern Thailand: A ten-year retrospective cross-sectional study.

IF 2.3 4区 医学 Q3 ALLERGY
Suwannee Uthaisangsook, Nichayada Hirunwattana, Chayanis Kajornrojanaruk, Nadda Padsee
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引用次数: 0

Abstract

Background: The prevalence and etiology of anaphylaxis vary based on geographic regions, study design, and definition used. Anaphylaxis leading to emergency department visits and hospitalizations has increased worldwide.

Objective: The prevalence and etiology of anaphylaxis vary based on geographic regions, study design, and definition used. Anaphylaxis leading to emergency department visits and hospitalizations has increased worldwide.

Methods: A cross-sectional retrospective analysis of medical records from patients with ICD-10 confirmed anaphylaxis was performed at Naresuan University Hospital between March 2011 and February 2021.

Results: We identified 439 anaphylaxis episodes in 381 patients within 10 years. The average annual occurrence rates of anaphylactic episodes were 25.0 per 100,000 outpatient and emergency department visits and 11.2 per 100,000 inpatient visits. Both pediatric and adult anaphylaxis events increased annually, from 13.3 (children: 20.5, adults: 12.4) in 2012 to 46.6 (children: 52.6, adults: 46.1) episodes per 100,000 visits in 2021. Peak incidence was observed in adolescents and young adults. Food was the most common trigger, with shrimp and fried insects being predominant. Risk factors for severe anaphylaxis were underlying cardiovascular diseases, drug triggers, and wheezing. Epinephrine was administered in 98.4% of all episodes. Although, there were no fatalities, only 11.4% of patients received prescriptions for self-injectable epinephrine.

Conclusion: The study underscores an increasing trend of anaphylaxis affecting both children and adults in lower northern Thailand, with shrimp and fried insects as common triggers.

泰国下北部三级医院过敏性休克的特征:一项为期十年的回顾性横断面研究。
背景:过敏性休克的发病率和病因因地理区域、研究设计和所用定义而异。过敏性休克导致的急诊就诊和住院治疗在全球范围内有所增加:过敏性休克的发病率和病因因地理区域、研究设计和所用定义而异。导致急诊就诊和住院治疗的过敏性休克在全球呈上升趋势:方法:2011 年 3 月至 2021 年 2 月期间,纳瑞宣大学医院对 ICD-10 确诊的过敏性休克患者的病历进行了横断面回顾性分析:我们在 10 年内发现了 381 名患者的 439 次过敏性休克。过敏性休克的年平均发生率为每 10 万名门诊和急诊患者中有 25.0 例,每 10 万名住院患者中有 11.2 例。儿童和成人过敏性休克事件的发生率逐年上升,从 2012 年的每 10 万人次 13.3 例(儿童:20.5 例,成人:12.4 例)上升到 2021 年的每 10 万人次 46.6 例(儿童:52.6 例,成人:46.1 例)。发病高峰出现在青少年和年轻成年人中。食物是最常见的诱发因素,主要是虾和油炸昆虫。导致严重过敏性休克的风险因素包括潜在的心血管疾病、药物诱因和喘息。98.4%的过敏性休克患者使用了肾上腺素。虽然没有死亡病例,但只有 11.4% 的患者获得了自我注射肾上腺素的处方:这项研究表明,在泰国北部下游地区,儿童和成人过敏性休克的发病率呈上升趋势,虾和油炸昆虫是常见的诱发因素。
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来源期刊
CiteScore
12.80
自引率
0.00%
发文量
74
审稿时长
>12 weeks
期刊介绍: The Asian Pacific Journal of Allergy and Immunology (APJAI) is an online open access journal with the recent impact factor (2018) 1.747 APJAI published 4 times per annum (March, June, September, December). Four issues constitute one volume. APJAI publishes original research articles of basic science, clinical science and reviews on various aspects of allergy and immunology. This journal is an official journal of and published by the Allergy, Asthma and Immunology Association, Thailand. The scopes include mechanism, pathogenesis, host-pathogen interaction, host-environment interaction, allergic diseases, immune-mediated diseases, epidemiology, diagnosis, treatment and prevention, immunotherapy, and vaccine. All papers are published in English and are refereed to international standards.
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