Trends in drug overdose deaths among adults 65 years of age and older in Canada (2000–2022)

Sameer Imtiaz , Farihah Ali , Nat Kaminski , Cayley Russell , Jürgen Rehm
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Abstract

Background

Although young adults and middle-aged adults have borne the brunt of the drug overdose crisis in Canada, older adults are also at an increased risk of harms. We examined trends in drug overdose deaths and opioid overdose deaths among adults 65 years of age and older.

Methods

Age-standardized rates of drug overdose deaths in Canada (2000–2022) and of opioid overdose deaths in Ontario (2003–2021) were computed. Drug overdose deaths were based on vital statistics registries, while opioid overdose deaths were based on toxicologic testing. Trends were characterized using joinpoint regression.

Results

Drug overdose deaths among adults 65 years of age and older in Canada rose from 4.3 to 9.9 deaths per million in the entire population between 2000 and 2022 (Average Annual Percentage Change [AAPC; 95 % CI]: 3.1 % [2.6 %-3.6 %]). Increases were observed in males (AAPC [95 % CI]: 4.0 % [3.1 %-4.9 %]), females (2.1 % [1.0 %-3.2 %]) and unintentional deaths (6.0 % [1.0 %-11.3 %]) after stratification by sex and manner of death. Opioid overdose deaths among adults 65 years of age and older in Ontario increased from 1.5 to 5.2 deaths per million in the entire population between 2003 and 2021 (AAPC [95 % CI]: 7.5 % [4.5 %-10.5 %]).

Conclusions

Drug overdose deaths more than doubled in Canada and opioid overdose deaths more than tripled in Ontario among adults 65 years of age and older during the past two decades. These findings indicate a need for education of patients, prioritization of harm reduction interventions, screening, intervention and treatment and adherence to prescribing guidelines.

加拿大 65 岁及以上成年人吸毒过量死亡趋势(2000-2022 年)
背景虽然在加拿大,年轻人和中年人在吸毒过量危机中首当其冲,但老年人受到伤害的风险也在增加。我们研究了 65 岁及以上成年人药物过量死亡和阿片类药物过量死亡的趋势。方法计算了加拿大药物过量死亡的年龄标准化比率(2000-2022 年)和安大略省阿片类药物过量死亡的年龄标准化比率(2003-2021 年)。吸毒过量死亡病例以生命统计登记为依据,而阿片类药物过量死亡病例则以毒理学检测为依据。结果2000年至2022年间,加拿大65岁及以上成年人药物过量死亡人数从每百万人中4.3例上升至9.9例(平均年百分比变化[AAPC;95 % CI]:3.1 % [2.6 %-3.6 %])。按性别和死亡方式分层后,男性(AAPC [95 % CI]: 4.0 % [3.1 %-4.9 %])、女性(2.1 % [1.0 %-3.2 %])和意外死亡(6.0 % [1.0 %-11.3 %])的死亡率均有所上升。2003年至2021年期间,安大略省65岁及以上成年人中阿片类药物过量死亡的人数从每百万人中1.5例增加到5.2例(AAPC [95 % CI]:7.5 % [4.5 %-10.5 %])。结论在过去二十年中,加拿大65岁及以上成年人中药物过量死亡的人数增加了一倍多,而安大略省65岁及以上成年人中阿片类药物过量死亡的人数增加了两倍多。这些研究结果表明,有必要对患者进行教育,优先采取减少伤害的干预措施,进行筛查、干预和治疗,并遵守处方指南。
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来源期刊
Drug and alcohol dependence reports
Drug and alcohol dependence reports Psychiatry and Mental Health
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