{"title":"A review of fluorescent peptide-based chemosensors with selectivity for metal ions","authors":"Hamed Barzinmehr , Sorour Ramezanpour , Pezhman Shiri , Elmira Meghrazi Ahadi , Soheil Mohammadi , Faezeh Yazdian , Pedram Tavatoni","doi":"10.1016/j.ccr.2024.216055","DOIUrl":null,"url":null,"abstract":"<div><p>The exposure of certain metal ions poses significant risks to environmental and biological systems, prompting extensive research among chemists over the past few decades in the design and synthesis of chemosensors capable of sensing and quantifying these chemical species. Fluorescence techniques, known for their high sensitivity, have emerged as excellent tools for advancing chemosensor development. The appeal of peptide-based chemosensors lies in their remarkable biocompatibility, water solubility, low toxicity, and convenient conjugation to relevant biological macromolecules. These attributes position them as valuable tools for the sensing and estimation of biochemical species. In this review, different kinds of fluorescent peptide-based chemosensors that are selective for metal ions are examined, and their coordination modes, detecting methods, and synthesis pathways for fluorophore conjugation with peptide chains are explained, as well.</p></div>","PeriodicalId":289,"journal":{"name":"Coordination Chemistry Reviews","volume":null,"pages":null},"PeriodicalIF":20.3000,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Coordination Chemistry Reviews","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0010854524004016","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, INORGANIC & NUCLEAR","Score":null,"Total":0}
引用次数: 0
Abstract
The exposure of certain metal ions poses significant risks to environmental and biological systems, prompting extensive research among chemists over the past few decades in the design and synthesis of chemosensors capable of sensing and quantifying these chemical species. Fluorescence techniques, known for their high sensitivity, have emerged as excellent tools for advancing chemosensor development. The appeal of peptide-based chemosensors lies in their remarkable biocompatibility, water solubility, low toxicity, and convenient conjugation to relevant biological macromolecules. These attributes position them as valuable tools for the sensing and estimation of biochemical species. In this review, different kinds of fluorescent peptide-based chemosensors that are selective for metal ions are examined, and their coordination modes, detecting methods, and synthesis pathways for fluorophore conjugation with peptide chains are explained, as well.
期刊介绍:
Coordination Chemistry Reviews offers rapid publication of review articles on current and significant topics in coordination chemistry, encompassing organometallic, supramolecular, theoretical, and bioinorganic chemistry. It also covers catalysis, materials chemistry, and metal-organic frameworks from a coordination chemistry perspective. Reviews summarize recent developments or discuss specific techniques, welcoming contributions from both established and emerging researchers.
The journal releases special issues on timely subjects, including those featuring contributions from specific regions or conferences. Occasional full-length book articles are also featured. Additionally, special volumes cover annual reviews of main group chemistry, transition metal group chemistry, and organometallic chemistry. These comprehensive reviews are vital resources for those engaged in coordination chemistry, further establishing Coordination Chemistry Reviews as a hub for insightful surveys in inorganic and physical inorganic chemistry.