Risk factors for infection in patients undergoing knee arthroscopy: A Systematic Review and Meta-analysis.

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC
Yuanhu Lei, Yuhuan Zeng, Zhengyu Li, Zhihong Xiao, Guojun Tang, Yi Liu, Changming Xiao, Mingjiang Luo, Huyong Yan, Hao Chen, Xiaoxu Wang
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引用次数: 0

Abstract

Purpose: The primary aim was to determine the risk of infection after knee arthroscopy and to evaluate the risk factors for surgical site infection (SSI).

Methods: The PubMed/Medline, Embase and Cochrane Library databases were systematically searched, as were the reference lists of previous systematic reviews and meta-analysis manual studies. A random-effects model was used to calculate the estimated pooled odds ratio (OR).

Results: A total of 38,321 potential articles met the initial inclusion criteria. After a review of the titles, abstracts and full texts, the remaining 41 articles were included in the final analysis. We identified 9,089,578 patients who underwent knee arthroscopy in 41 articles. High-quality (class I) evidence showed that autografts (cruciate ligament reconstruction) (OR, 2.66% CI, 1.84-3.86) or high procedure complexity (OR, 2.02;95% CI, 1.69-2.43) had a higher risk of infection, while medium-quality (class II or class III) evidence showed that obesity (BMI ≥ 30 kg/m2) (OR, 1.27; 95% CI, 1.08-1.49) or male (OR, 1.52; 95% CI, 1.32-1.75) or diabetes (OR, 1.71; 95% CI, 1.36-2.14) or tobacco use (OR, 1.65; 95% CI, 1.38-1.97) or preoperative steroid use (OR, 3.41; 95% CI, 2.10-5.54) had a higher risk of infection. The meta-analysis showed that there was no association between age or antibiotic prophylaxis and infection incidence.

Conclusions: The meta-analysis showed that significant risk factors for infection after knee arthroscopy included obesity, male sex, diabetes, tobacco use, high procedure complexity, graft type, and preoperative steroid use.

Level of evidence: Level IV, systematic review of Level III and Level IV studies.

膝关节镜手术患者感染的风险因素:系统回顾和元分析。
目的:主要目的是确定膝关节镜手术后的感染风险,并评估手术部位感染(SSI)的风险因素:方法:系统检索了 PubMed/Medline、Embase 和 Cochrane 图书馆数据库,以及以往系统综述和荟萃分析手册研究的参考文献列表。结果:共有 38,321 篇潜在文章符合初步纳入标准。在对标题、摘要和全文进行审查后,剩余的 41 篇文章被纳入最终分析。我们在 41 篇文章中确定了 9089578 名接受膝关节镜手术的患者。高质量(I级)证据显示,自体移植物(十字韧带重建)(OR,2.66% CI,1.84-3.86)或手术复杂度高(OR,2.02;95% CI,1.69-2.43)的感染风险更高,而中等质量(II级或III级)证据显示,肥胖(体重指数≥30 kg/m2)(OR,1.27;95% CI,1.08-1.49)或男性(OR,1.52;95% CI,1.32-1.75)或糖尿病(OR,1.71;95% CI,1.36-2.14)或吸烟(OR,1.65;95% CI,1.38-1.97)或术前使用类固醇(OR,3.41;95% CI,2.10-5.54)有更高的感染风险。荟萃分析表明,年龄或抗生素预防与感染发生率之间没有关联:荟萃分析表明,膝关节镜手术后感染的重要风险因素包括肥胖、男性、糖尿病、吸烟、手术复杂度高、移植物类型和术前使用类固醇:IV级,对III级和IV级研究的系统回顾。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
7.20
自引率
4.30%
发文量
567
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