Associations of accelerometer-measured sleep duration with incident cardiovascular disease and cardiovascular mortality.

IF 5.6 2区医学 Q1 Medicine

Sleep Pub Date : 2024-11-08 DOI:10.1093/sleep/zsae157

Mingqing Zhou, Yannis Yan Liang, Sizhi Ai, Hongliang Feng, Yujing Zhou, Yaping Liu, Jihui Zhang, Fujun Jia, Binbin Lei

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引用次数: 0

Abstract

Study objectives: This study aimed to determine the associations between accelerometer-measured sleep durations and the risks of incident cardiovascular disease (CVD) and CVD-related mortality.

Methods: A total of 92 261 participants (mean age: 62.4 ± 7.8 years, 56.4% female) were included in UK Biobank between 2013 and 2015. Average daily sleep durations were measured using wrist-worn accelerometers over a 7-day period. Sleep durations were categorized as <7 hours/day, 7-9 hours/day (reference), and >9 hours/day. The incidence of CVD and CVD-related mortality were ascertained by hospital records and death registries.

Results: During a median follow-up period of 7.0 years, a total of 13 167 participants developed CVD, and 1079 participants died of CVD. Compared with a sleep duration 7-9 hours/day, an accelerometer-measured sleep duration <7 hours/day but not >9 hours/day was associated with higher risks of incident CVD (HR 1.06, 95% CI: 1.02 to 1.10), CVD-related mortality (HR 1.29, 95% CI: 1.14 to 1.47), coronary heart disease (HR 1.11, 95% CI: 1.03 to 1.19), myocardial infarction (HR 1.14, 95% CI: 1.03 to 1.27), heart failure (HR 1.20, 95% CI: 1.08 to 1.34), and atrial fibrillation (HR 1.15, 95% CI: 1.07 to 1.24). A curvilinear dose‒response pattern was observed between accelerometer-measured sleep durations and incident CVD (poverall < .001), with L-shaped associations found for incident CVD and CVD-related mortality.

Conclusions: An accelerometer-measured sleep duration of <7 hours/day but not >9 hours/day was associated with elevated risks of incident CVD and CVD-related mortality. Maintaining adequate sleep may help promote cardiovascular health.

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加速计测量的睡眠时间与心血管疾病和心血管疾病死亡率的关系

研究目的本研究旨在确定加速度计测量的睡眠时间与心血管疾病（CVD）发病风险和CVD相关死亡率之间的关联：2013年至2015年期间，英国生物数据库共纳入了92261名参与者（平均年龄：62.4±7.8岁，56.4%为女性）。使用腕戴式加速度计测量了为期七天的平均日睡眠时间。睡眠时间被归类为 9 小时/天。心血管疾病发病率和心血管疾病相关死亡率由医院记录和死亡登记确定：中位随访期为 7.0 年，共有 13,167 人患上心血管疾病，1,079 人死于心血管疾病。与睡眠时间为 7-9 小时/天的人相比，加速度计测量的睡眠时间为 9 小时/天的人发生心血管疾病（HR 1.06，95% CI：1.02-1.10）、心血管疾病相关死亡（HR 1.29，95% CI：1.14-1.47）、冠心病（HR 1.11，95% CI：1.03-1.19）、心肌梗死（HR 1.14，95% CI：1.03-1.27）、心力衰竭（HR 1.20，95% CI：1.08-1.34）和心房颤动（HR 1.15，95% CI：1.07-1.24）。加速度计测量的睡眠时间与心血管疾病发病率之间呈曲线剂量反应模式（结论：加速度计测量的睡眠时间与心血管疾病发病率之间呈曲线剂量反应模式（结论：加速度计测量的睡眠时间与心血管疾病发病率之间呈曲线剂量反应模式）：加速度计测量的睡眠时间为 9 小时/天与心血管疾病发病风险和心血管疾病相关死亡率升高有关。保持充足的睡眠有助于促进心血管健康。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Sleep Medicine-Neurology (clinical)

CiteScore

8.70

自引率

10.70%

发文量

期刊介绍： SLEEP® publishes findings from studies conducted at any level of analysis, including: Genes Molecules Cells Physiology Neural systems and circuits Behavior and cognition Self-report SLEEP® publishes articles that use a wide variety of scientific approaches and address a broad range of topics. These may include, but are not limited to: Basic and neuroscience studies of sleep and circadian mechanisms In vitro and animal models of sleep, circadian rhythms, and human disorders Pre-clinical human investigations, including the measurement and manipulation of sleep and circadian rhythms Studies in clinical or population samples. These may address factors influencing sleep and circadian rhythms (e.g., development and aging, and social and environmental influences) and relationships between sleep, circadian rhythms, health, and disease Clinical trials, epidemiology studies, implementation, and dissemination research.