Analyzing the infertility burden of polycystic ovarian syndrome in China: A comprehensive age-period-cohort analysis with future burden prediction (1990-2030).

IF 2 4区 医学 Q3 ENDOCRINOLOGY & METABOLISM
Gynecological Endocrinology Pub Date : 2024-12-01 Epub Date: 2024-07-11 DOI:10.1080/09513590.2024.2362251
DongYi Shen, Yang Wang, PanWei Hu, Cong Qi, Hong Yang
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引用次数: 0

Abstract

Objective: Polycystic ovarian syndrome (PCOS) is a common but complex endocrine disorder widely linked to infertility and miscarriage. This study assessed the correlation between PCOS and infertility.

Methods: Using the latest data from the Global Burden of Disease 2019 database, we conducted an in-depth assessment of the disease burden attributed to PCOS in China. This analysis was performed using the joinpoint regression, age-period-cohort, and autoregressive integrated moving average (ARIMA) models.

Results: Between 1990-2019, an upward trend was observed in the age-standardized prevalence of PCOS-related female infertility in China. Joinpoint regression analysis revealed an increasing trend in the age-standardized prevalence of PCOS-related female infertility burden indicators as well as the average annual percentage change and annual percentage change across all age groups in China. In terms of the cohort effect, the period rate ratios associated with the age-standardized prevalence of PCOS-related infertility increased steadily over time. The ARIMA model predicted a relatively swift upward trend in the age-standardized prevalence of PCOS-related infertility in China from 2020-2030.

Conclusion: The age-standardized prevalence of PCOS-related female infertility in China has increased between 1990-2019. The ARIMA model predicted that the age-standardized prevalence of this disease may continue to increase over the next decade. This study can increase the public's attention, improve women's health awareness, and have a certain significance for reducing female infertility related to PCOS.

中国多囊卵巢综合征不孕不育负担分析:综合年龄段队列分析及未来负担预测(1990-2030 年)。
目的:多囊卵巢综合征(PCOS多囊卵巢综合征(PCOS)是一种常见但复杂的内分泌疾病,与不孕和流产广泛相关。本研究评估了多囊卵巢综合征与不孕症之间的相关性:方法:利用《2019 年全球疾病负担》数据库中的最新数据,我们对中国多囊卵巢综合征导致的疾病负担进行了深入评估。结果:1990-2019年间,中国多囊卵巢综合征的发病率呈上升趋势:结果:1990-2019 年间,中国多囊卵巢综合征相关女性不孕症的年龄标准化患病率呈上升趋势。连接点回归分析显示,中国多囊卵巢综合征相关女性不孕负担指标的年龄标准化患病率以及各年龄组的年均百分比变化和年均百分比变化均呈上升趋势。在队列效应方面,与多囊卵巢综合症相关不孕症年龄标准化患病率相关的期间比率随着时间的推移稳步上升。根据 ARIMA 模型预测,2020-2030 年期间,中国多囊卵巢综合征相关不孕症的年龄标准化患病率将呈较快的上升趋势:结论:1990-2019年间,中国PCOS相关女性不孕症的年龄标准化患病率呈上升趋势。ARIMA模型预测,该疾病的年龄标准化患病率在未来十年内可能会继续上升。本研究可提高公众的关注度,提高女性的健康意识,对减少多囊卵巢综合征相关女性不孕症的发生具有一定的意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Gynecological Endocrinology
Gynecological Endocrinology 医学-妇产科学
CiteScore
4.40
自引率
5.00%
发文量
137
审稿时长
3-6 weeks
期刊介绍: Gynecological Endocrinology , the official journal of the International Society of Gynecological Endocrinology, covers all the experimental, clinical and therapeutic aspects of this ever more important discipline. It includes, amongst others, papers relating to the control and function of the different endocrine glands in females, the effects of reproductive events on the endocrine system, and the consequences of endocrine disorders on reproduction
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