Biomarker responses in Danio rerio following an acute exposure (96 h) to e-waste leachate.

IF 2.4 4区环境科学与生态学 Q2 ECOLOGY

Ecotoxicology Pub Date : 2024-10-01 Epub Date: 2024-07-12 DOI:10.1007/s10646-024-02784-6

A Rielly, S Dahms-Verster, R Greenfield

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Abstract

Electronic waste (e-waste) has been identified as an emerging pollutant and is the fastest growing waste stream at the present time. Significant technological development and modernization within the last decade has led to the rapid accumulation of outdated, broken and unwanted electrical and electronic equipment (EEE). Electronic products mainly consist of a range of metal containing components that, when disposed of improperly, could result in metal constituents leached into the environment and posing a health risk to humans and animals alike. Metal exposure can induce oxidative stress in organisms, which could lead to synergistic, antagonistic and additive effects. The metals found highest in abundance in the simulated e-waste leachate, were nickel (Ni), barium (Ba), zinc (Zn), lithium (Li), iron (Fe), aluminium (Al) and copper (Cu). An acute exposure study was conducted over a 96 h period to determine the potential toxicity of e-waste on the test organism Danio rerio. Biomarker analysis results to assess the biochemical and physiological effects induced by e-waste leachate, showed a statistically significant effect induced on acetylcholinesterase activity, superoxide dismutase, catalase activity, reduced glutathione content, glutathione s-transferase, malondialdehyde and glucose energy available. The Integrated Biomarker Response (IBRv2) analysis revealed a greater biomarker response induced as the exposure concentration of e-waste leachate increased.

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Danio rerio 急性接触（96 小时）电子废物沥滤液后的生物标志物反应。

电子废物（e-waste）已被确定为一种新出现的污染物，是目前增长最快的废物流。在过去十年中，技术的大幅发展和现代化导致过时、破损和无用的电气和电子设备（EEE）迅速积累。电子产品主要由一系列含金属成分的部件组成，如果处置不当，可能导致金属成分渗入环境，对人类和动物的健康构成威胁。接触金属会对生物体造成氧化应激，从而产生协同、拮抗和叠加效应。在模拟电子废物沥滤液中发现的含量最高的金属是镍（Ni）、钡（Ba）、锌（Zn）、锂（Li）、铁（Fe）、铝（Al）和铜（Cu）。进行了一项为期 96 小时的急性接触研究，以确定电子废物对测试生物 Danio rerio 的潜在毒性。生物标记分析结果显示，电子垃圾渗滤液对乙酰胆碱酯酶活性、超氧化物歧化酶、过氧化氢酶活性、还原型谷胱甘肽含量、谷胱甘肽转移酶、丙二醛和葡萄糖能量的影响具有统计学意义。综合生物标志物反应（IBRv2）分析表明，随着接触电子垃圾渗滤液浓度的增加，诱发的生物标志物反应也越大。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ecotoxicology 环境科学-毒理学

CiteScore

5.30

自引率

3.70%

发文量

107

审稿时长

4.7 months

期刊介绍： Ecotoxicology is an international journal devoted to the publication of fundamental research on the effects of toxic chemicals on populations, communities and terrestrial, freshwater and marine ecosystems. It aims to elucidate mechanisms and processes whereby chemicals exert their effects on ecosystems and the impact caused at the population or community level. The journal is not biased with respect to taxon or biome, and papers that indicate possible new approaches to regulation and control of toxic chemicals and those aiding in formulating ways of conserving threatened species are particularly welcome. Studies on individuals should demonstrate linkage to population effects in clear and quantitative ways. Laboratory studies must show a clear linkage to specific field situations. The journal includes not only original research papers but technical notes and review articles, both invited and submitted. A strong, broadly based editorial board ensures as wide an international coverage as possible.