Cyclamen libanoticum is a Novel Bioresource for Green Silver Nanoparticles with Antibacterial and Antioxidant Capabilities

IF 1.4 4区材料科学 Q4 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Current Nanoscience Pub Date : 2024-07-10 DOI:10.2174/0115734137310446240616164456

Zeinab Hachem, Rayan Kashmar, Alaa Abdallah, Ramadan Awad, Mahmoud Khalil

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引用次数: 0

Abstract

Background: It has become essential to look into alternatives that effectively stop bacterial infections due to the exponential rise in antibiotic resistance. The field of nanotechnology has made significant strides in development by surmounting obstacles that have impeded success and advancement in other fields. Nanoparticles (NPs) are the key component in the burgeoning field of nanotechnology. Objective: Cyclamen libanoticum leaf extract (CLE) was used as a reducing and capping agent, with silver nitrate (AgNO3) solution as a precursor for synthesizing silver nanoparticles (CLEAgNPs). This study aimed to generate green silver nanoparticles (AgNPs) and assess their antioxidant and antibacterial capacities. Methods: CLE-AgNPs were characterized utilizing UV–vis spectrometry, X-ray diffraction (XRD), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR), and photoluminescence (PL). Using the radical scavenging assay 2,2-diphenyl-1-picrylhydrazyl (DPPH), the antioxidant activity of CLEAgNPs was evaluated. Several assays were employed to examine the antibacterial effect of CLE-AgNPs against various gram-positive and negative bacteria. Results: Upon analysis, the synthesis revealed 17 nm face-centered cubic CLE-AgNPs (λmax= 431 nm). CLE-AgNPs manifested noticeable antioxidant activity and prominent inhibitory effects on the tested bacteria. The minimum inhibitory concentration (MIC) of the CLE-AgNPs was 31.25 μg/mL for the eight bacterial species. Besides, the results revealed that CLE-AgNPs effectively suppressed the development of bacterial biofilms and could eradicate them. Conclusion: The present investigation introduced Cyclamen libanoticum as a novel bioresource into green chemistry to produce AgNPs with antibacterial and antioxidant capabilities.

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仙客来是具有抗菌和抗氧化能力的绿色银纳米粒子的新型生物资源

背景：由于抗生素耐药性呈指数级增长，研究能有效阻止细菌感染的替代品已变得十分必要。纳米技术领域克服了阻碍其他领域取得成功和进步的障碍，取得了长足的发展。纳米粒子（NPs）是新兴纳米技术领域的关键组成部分。目的以仙客来叶提取物（CLE）为还原剂和封端剂，硝酸银（AgNO3）溶液为前驱体，合成银纳米粒子（CLEAgNPs）。本研究旨在生成绿色银纳米粒子（AgNPs），并评估其抗氧化和抗菌能力。方法：利用紫外可见光谱、X 射线衍射（XRD）、透射电子显微镜（TEM）、X 射线光电子能谱（XPS）、傅立叶变换红外光谱（FTIR）和光致发光（PL）对 CLE-AgNPs 进行表征。利用自由基清除试验 2,2-二苯基-1-苦基肼（DPPH）评估了 CLEAgNPs 的抗氧化活性。此外，还采用了多种检测方法来研究 CLEAgNPs 对各种革兰氏阳性和阴性细菌的抗菌效果。结果：经分析，合成的 CLE-AgNPs 为 17 纳米面心立方体（λmax= 431 纳米）。CLE-AgNPs 具有明显的抗氧化活性，对受试细菌有显著的抑制作用。CLE-AgNPs 对八种细菌的最小抑菌浓度（MIC）为 31.25 μg/mL。此外，研究结果表明，CLE-AgNPs 能有效抑制细菌生物膜的发展，并能根除它们。结论本研究将仙客来作为一种新型生物资源引入绿色化学，生产出具有抗菌和抗氧化能力的 AgNPs。

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来源期刊

Current Nanoscience 工程技术-材料科学：综合

CiteScore

3.50

自引率

6.70%

发文量

审稿时长

4.4 months

期刊介绍： Current Nanoscience publishes (a) Authoritative/Mini Reviews, and (b) Original Research and Highlights written by experts covering the most recent advances in nanoscience and nanotechnology. All aspects of the field are represented including nano-structures, nano-bubbles, nano-droplets and nanofluids. Applications of nanoscience in physics, material science, chemistry, synthesis, environmental science, electronics, biomedical nanotechnology, biomedical engineering, biotechnology, medicine and pharmaceuticals are also covered. The journal is essential to all researches involved in nanoscience and its applied and fundamental areas of science, chemistry, physics, material science, engineering and medicine. Current Nanoscience also welcomes submissions on the following topics of Nanoscience and Nanotechnology: Nanoelectronics and photonics Advanced Nanomaterials Nanofabrication and measurement Nanobiotechnology and nanomedicine Nanotechnology for energy Sensors and actuator Computational nanoscience and technology.