Moxibustion combined with guasha therapy for recurrent neutropenia following multiple cycles of chemotherapy of ovarian cancer: A case report

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-07-06 DOI:10.1016/j.explore.2024.103031

Weina Zhang, Jingnan Xu, Yuxiang Wan, Ming Yang, Jinchang Huang

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引用次数: 0

Abstract

Neutropenia, a common side effect of chemotherapy for ovarian cancer, was observed in a 47-year-old female patient undergoing a six-cycle chemotherapy regimen. She experienced recurrent neutropenia and leukopenia but refused granulocyte colony-stimulating factor (G-CSF) due to severe bone pain and high costs. Moxibustion combined with guasha therapy (MGT) was administered each time neutropenia occurred. The treatment involved guasha therapy on the bladder meridian (BL) and the governor vessel (GV), followed by moxibustion at Zhongwan (CV 12), Guanyuan (CV 4), and Shenzhu (GV 12) points over 2–3 days. This approach led to the recovery of neutrophil and leukocyte counts, enabling the patient to complete six chemotherapy cycles without G-CSF. These findings suggest that MGT may enhance neutrophil and leukocyte counts in patients with chemotherapy-induced myelosuppression, presenting a potential alternative for those intolerant to G-CSF. However, further high-quality research is needed to confirm its efficacy.

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艾灸结合刮痧治疗卵巢癌多周期化疗后复发性中性粒细胞减少症：病例报告。

中性粒细胞减少症是卵巢癌化疗的常见副作用，一名 47 岁的女性患者接受了六周期化疗。她反复出现中性粒细胞减少症和白细胞减少症，但由于严重的骨痛和高昂的费用，她拒绝使用粒细胞集落刺激因子（G-CSF）。每次出现中性粒细胞减少时，她都会进行艾灸结合刮痧疗法（MGT）。治疗方法包括在膀胱经（BL）和督脉（GV）上进行刮痧治疗，然后在中脘（CV 12）、关元（CV 4）和神阙（GV 12）穴位上艾灸 2-3 天。这种方法使患者的中性粒细胞和白细胞数量得到恢复，使其能够在不使用 G-CSF 的情况下完成六个化疗周期。这些研究结果表明，MGT 可以提高化疗引起的骨髓抑制患者的中性粒细胞和白细胞数量，为那些对 G-CSF 不耐受的患者提供了一种潜在的替代疗法。不过，还需要进一步的高质量研究来证实其疗效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.