Understanding Preferences for Visualized New and Future HIV Prevention Products Among Gay, Bisexual and Other Men Who Have Sex with Men in the Southern United States: A Mixed-Methods Study.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
Damian J Denson, Ayana Stanley, Laura Randall, Casey Langer Tesfaye, Daniela Glusberg, Jessica Cardo, Adrian R King, Bryan Gale, Valerie Betley, Alisú Schoua-Glusberg, Paula M Frew
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Abstract

Men who have sex with men (MSM) are vulnerable to HIV infection. Although daily oral pre-exposure prophylaxis (PrEP) prevents HIV among MSM, its usage remains low. We conducted virtual in-depth interviews (IDIs) and focus groups (FGs) with Black, Hispanic/Latino, and White MSM consisting of current PrEP users and those aware of but not currently using PrEP. We delved into their preferences regarding six emerging PrEP products: a weekly oral pill, event-driven oral pills, anal douche/enema, anal suppository, long-acting injection, and a skin implant. Our mixed methods analysis involved inductive content analysis of transcripts for thematic identification and calculations of preferences. Among the sample (n = 98), the weekly oral pill emerged as the favored option among both PrEP Users and PrEP Aware IDI participants. Ranking exercises during FGs also corroborated this preference, with the weekly oral pill being most preferred. However, PrEP Users in FGs leaned toward the long-acting injectable. Conversely, the anal suppository and douche/enema were the least preferred products. Overall, participants were open to emerging PrEP products and valued flexibility but expressed concerns about limited protection for products designed solely for receptive sex. Public health practitioners should tailor recommendations based on individuals' current sexual behaviors and long-term vulnerability to infection.

了解美国南部男同性恋、双性恋和其他男男性行为者对可视化新产品和未来艾滋病预防产品的偏好:混合方法研究》。
男男性行为者(MSM)很容易感染艾滋病毒。尽管每日口服暴露前预防药物(PrEP)可预防 MSM 感染艾滋病毒,但其使用率仍然很低。我们对黑人、西班牙裔/拉丁美洲人和白人 MSM 进行了虚拟深度访谈 (IDI) 和焦点小组 (FG),访谈对象包括目前使用 PrEP 的人和了解但目前未使用 PrEP 的人。我们深入研究了他们对六种新兴 PrEP 产品的偏好:每周口服药、事件驱动口服药、肛门冲洗器/灌肠器、肛门栓剂、长效注射剂和皮肤植入剂。我们的混合方法分析包括对记录誊本进行归纳内容分析,以确定主题并计算偏好。在样本(n = 98)中,每周口服避孕药成为 PrEP 使用者和 PrEP 意识 IDI 参与者的首选。在论坛交流期间进行的排序活动也证实了这一偏好,每周口服一次药片最受青睐。然而,在专题小组讨论中,PrEP 使用者倾向于长效注射剂。相反,肛门栓剂和冲洗/灌肠剂是最不受欢迎的产品。总体而言,参与者对新出现的 PrEP 产品持开放态度,并重视产品的灵活性,但对仅为接受性 行为设计的产品的有限保护能力表示担忧。公共卫生从业人员应根据个人当前的性行为和长期易受感染性来定制建议。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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