Intravenous fluid therapy compared to no treatment following blood donation in cats: a randomised controlled trial

IF 1.7 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Small Animal Practice Pub Date : 2024-07-10 DOI:10.1111/jsap.13760

M. Guedra Allais, K. Humm

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引用次数: 0

Abstract

Objectives

There is currently no consensus regarding the use of intravenous fluid therapy in feline patients post-blood donation in veterinary medicine. The primary aim of this study was to determine whether blood donation can be performed safely without post-donation intravenous fluid therapy. The secondary aim was to report owner-noted post-donation changes.

Materials and Methods

The study aimed to enrol 100 conscious feline blood donations by client-owned cats performed at a veterinary teaching hospital. Donors were randomised to either receive intravenous compound sodium lactate (twice the volume of blood donated over 2 hours) immediately after blood donation, or to receive no post-blood donation intravenous fluid therapy. Systolic blood pressure was measured non-invasively at 0, 60 and 120 minutes post-donation. Median blood pressures were compared between the two groups using a Shapiro-Wilk test. Owners were called the day following the donation to collect information on changes in their cat post-donation.

Results

One hundred cats were enrolled and the data of 97 cats were analysed; 46 who received intravenous fluid therapy and 51 who did not. Mean donation volume was 9.95 mL/kg for the intravenous fluid therapy group and 9.72 mL/kg for the non-intravenous fluid therapy group. At each time point, the median blood pressure did not differ significantly between the two groups. The main reported changes in both goups were bruising at the venepuncture site with 27.3% (12/44) in the IVFT group and 23.4% (9/37) in the no-IVFT group, and mild lethargy up to a maximum of 24 hours post donation with 11.4% (5/44) in the IVFT group and 18.9% (7/37) in the no-IVFT group.

Clinical Significance

This study suggests that the use of intravenous fluid therapy post-feline blood donation may not be necessary. This could mean reduced hospitalisation time for feline donors, possibly decreasing feline stress.

Abstract Image

查看原文本刊更多论文

猫献血后静脉输液治疗与不治疗的比较：随机对照试验。

目的：目前，兽医学界尚未就猫科动物献血后使用静脉输液疗法达成共识。本研究的主要目的是确定献血是否可以在不进行献血后静脉输液治疗的情况下安全进行。次要目的是报告猫主人记录的献血后变化：这项研究的目的是在一家兽医教学医院招募 100 名有意识的猫科动物献血者。献血者被随机分配为献血后立即接受静脉注射复合乳酸钠（两倍于献血量，持续 2 小时），或献血后不接受静脉输液治疗。在献血后 0 分钟、60 分钟和 120 分钟分别对收缩压进行无创测量。采用 Shapiro-Wilk 检验比较两组的中位血压。在捐赠后的第二天给猫的主人打电话，收集猫在捐赠后的变化信息：对 100 只猫进行了登记，并分析了 97 只猫的数据；其中 46 只接受了静脉输液治疗，51 只没有。静脉输液治疗组的平均捐献量为 9.95 mL/kg，非静脉输液治疗组的平均捐献量为 9.72 mL/kg。在每个时间点，两组的血压中位数均无显著差异。两组报告的主要变化是静脉穿刺部位瘀伤，静脉输液治疗组为 27.3%（12/44），非静脉输液治疗组为 23.4%（9/37）；轻度嗜睡，静脉输液治疗组为 11.4%（5/44），非静脉输液治疗组为 18.9%（7/37），最长达捐献后 24 小时：本研究表明，猫科动物献血后可能无需使用静脉输液疗法。临床意义：该研究表明，猫科动物献血后可能不需要使用静脉输液疗法，这意味着猫科动物献血者的住院时间缩短，可能会减轻猫科动物的压力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Small Animal Practice 农林科学-兽医学

CiteScore

3.30

自引率

6.20%

发文量

117

审稿时长

12-24 weeks

期刊介绍： Journal of Small Animal Practice (JSAP) is a monthly peer-reviewed publication integrating clinical research papers and case reports from international sources, covering all aspects of medicine and surgery relating to dogs, cats and other small animals. These papers facilitate the dissemination and implementation of new ideas and techniques relating to clinical veterinary practice, with the ultimate aim of promoting best practice. JSAP publishes high quality original articles, as well as other scientific and educational information. New developments are placed in perspective, encompassing new concepts and peer commentary. The target audience is veterinarians primarily engaged in the practise of small animal medicine and surgery. In addition to original articles, JSAP will publish invited editorials (relating to a manuscript in the same issue or a topic of current interest), review articles, which provide in-depth discussion of important clinical issues, and other scientific and educational information from around the world. The final decision on publication of a manuscript rests with the Editorial Board and ultimately with the Editor. All papers, regardless of type, represent the opinion of the authors and not necessarily that of the Editor, the Association or the Publisher. The Journal of Small Animal Practice is published on behalf of the British Small Animal Veterinary Association and is also the official scientific journal of the World Small Animal Veterinary Association