Vascular changes of the peripapillary choroidal area in the thyroid orbitopathy.

IF 1.4 4区医学 Q3 OPHTHALMOLOGY

International Ophthalmology Pub Date : 2024-07-11 DOI:10.1007/s10792-024-03111-y

Metin Unlu, Furkan Ozer, Hidayet Sener, Duygu Gulmez Sevim

{"title":"Vascular changes of the peripapillary choroidal area in the thyroid orbitopathy.","authors":"Metin Unlu, Furkan Ozer, Hidayet Sener, Duygu Gulmez Sevim","doi":"10.1007/s10792-024-03111-y","DOIUrl":null,"url":null,"abstract":"Purpose: The aim of this study was to investigate the peripapillary choroidal vascular changes in thyroid orbitopathy (TO).Methods: The study included 20 eyes of 10 patients with active TO (aTO), 30 eyes of 15 patients with inactive TO (inaTO) and 30 eyes of 30 healthy subjects. The peripapillary choroidal vascular change was assessed with peripapillary choroidal vascular index (pCVI), peripapillary choroidal luminal area (pLA), peripapillary choroidal stromal area (pSA), peripapillary total choroidal area (pTCA).Results: Compared to the control group, there was a reduction in the nasal and temporal areas of pCVI in both the aTO and inaTO groups (aTO vs control: nasal p = 0.001 and temporal p = 0.004; inaTO vs control: nasal p = 0.007 and temporal p < 0.001), while the inferior area was lower only in the inaTO group (p = 0.001). Compared to the other groups, the inaTO group exhibited a decrease pSA (vs aTO: total p = 0.004, inferior p = 0.02 and vs control: total p = 0.01, inferior p = 0.03), pLA (vs aTO: total p = 0.02, inferior p = 0.02, temporal p < 0.001 and vs control: total p = 0.002, inferior p < 0.001, temporal p < 0.001) and pTCA (vs aTO: total p = 0.009, inferior p = 0.01, temporal p < 0.001 and vs control: total p = 0.003, inferior p = 0.001, temporal p < 0.001).Conclusion: The horizontal area (nasal and temporal area) of the peripapillary choroidal vascular structure may be more sensitive than the vertical area in TO patients. The first affected quadrant of RPC-VD in the active TO may be the inferior quadrant. Structural or vascular choroidal changes may occur during the chronic or post-active phase of the disease.","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Ophthalmology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s10792-024-03111-y","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose: The aim of this study was to investigate the peripapillary choroidal vascular changes in thyroid orbitopathy (TO).

Methods: The study included 20 eyes of 10 patients with active TO (aTO), 30 eyes of 15 patients with inactive TO (inaTO) and 30 eyes of 30 healthy subjects. The peripapillary choroidal vascular change was assessed with peripapillary choroidal vascular index (pCVI), peripapillary choroidal luminal area (pLA), peripapillary choroidal stromal area (pSA), peripapillary total choroidal area (pTCA).

Results: Compared to the control group, there was a reduction in the nasal and temporal areas of pCVI in both the aTO and inaTO groups (aTO vs control: nasal p = 0.001 and temporal p = 0.004; inaTO vs control: nasal p = 0.007 and temporal p < 0.001), while the inferior area was lower only in the inaTO group (p = 0.001). Compared to the other groups, the inaTO group exhibited a decrease pSA (vs aTO: total p = 0.004, inferior p = 0.02 and vs control: total p = 0.01, inferior p = 0.03), pLA (vs aTO: total p = 0.02, inferior p = 0.02, temporal p < 0.001 and vs control: total p = 0.002, inferior p < 0.001, temporal p < 0.001) and pTCA (vs aTO: total p = 0.009, inferior p = 0.01, temporal p < 0.001 and vs control: total p = 0.003, inferior p = 0.001, temporal p < 0.001).

Conclusion: The horizontal area (nasal and temporal area) of the peripapillary choroidal vascular structure may be more sensitive than the vertical area in TO patients. The first affected quadrant of RPC-VD in the active TO may be the inferior quadrant. Structural or vascular choroidal changes may occur during the chronic or post-active phase of the disease.

Abstract Image

查看原文本刊更多论文

甲状腺眼眶病中毛细血管周围脉络膜区域的血管变化。

目的：本研究旨在探讨甲状腺眼眶病（TO）患者毛细血管周围脉络膜血管的变化：研究对象包括10名活动性甲状腺眼疾（aTO）患者的20只眼、15名非活动性甲状腺眼疾（inaTO）患者的30只眼以及30名健康受试者的30只眼。用毛细血管周围脉络膜血管指数（pCVI）、毛细血管周围脉络膜管腔面积（pLA）、毛细血管周围脉络膜基质面积（pSA）、毛细血管周围脉络膜总面积（pTCA）评估毛细血管周围脉络膜血管变化：与对照组相比，aTO 组和 inaTO 组的鼻腔和颞侧 pCVI 面积均有所减少（aTO 组与对照组相比：鼻腔 p = 0.001，颞侧 p = 0.004；inaTO 组与对照组相比：鼻腔 p = 0.007，颞侧 p = 0.004）：TO 患者脉络膜血管结构的水平区域（鼻腔和颞部）可能比垂直区域更敏感。活动性 TO 的 RPC-VD 第一个受影响的象限可能是下象限。脉络膜结构或血管变化可能发生在疾病的慢性期或活动后阶段。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

International Ophthalmology OPHTHALMOLOGY-

CiteScore

3.20

自引率

0.00%

发文量

451

期刊介绍： International Ophthalmology provides the clinician with articles on all the relevant subspecialties of ophthalmology, with a broad international scope. The emphasis is on presentation of the latest clinical research in the field. In addition, the journal includes regular sections devoted to new developments in technologies, products, and techniques.