Double Balloon Combined with Oxytocin in Labor Induction: Analysis of Multivariate Factors Affecting the Efficacy of Cervical Ripening.

IF 2.5 4区医学 Q2 OBSTETRICS & GYNECOLOGY

International Journal of Women's Health Pub Date : 2024-07-05 eCollection Date: 2024-01-01 DOI:10.2147/IJWH.S460853

Xian-Lin Wu, Hong-Yan Liu, Qiu-Hong Xiang, Zhuan Yin, Rong Zhou, Ye-Juan Wang, Bi-Yu Zhou, Fang Wang, Min Zhao, Mei Chen

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引用次数: 0

Abstract

Objective: Labor induction during the late trimester of pregnancy is a common option of terminating pregnancy by inducing uterine contractions through medication or cervical mechanical dilation. However, there are few researches on the factors influencing the effectiveness of cervical ripening balloon combined with oxytocin in inducing labor. To explore factors affecting the efficacy of cervical ripening double balloon combined with oxytocin in labor induction.

Methods: Using a convenient sampling method, this study retrospectively collected the clinical data of 230 pregnant women who underwent cervical ripening double balloon combined with oxytocin for labor induction in our hospital from September 2021 to August 2022. The included subjects were divided into a vaginal delivery group (n = 180) and a cesarean section group (n = 50) based on the delivery mode for comparing relevant indicators between the two groups.

Results: The presence of acute chorioamnionitis (OR = 1.456, 95% CI: 1.257-2.112), fetal distress (OR = 1.371, 95% CI: 1.331-2.633), and the placement of cervical ripening balloon catheter for >12h (OR = 1.563, 95% CI: 1.231-3.263) were risk factors for successful application of cervical ripening double balloon combined with oxytocin for labor induction in pregnant women; while multi-gravidity (OR = 0.736, 95% CI: 0.455-0.875) was a protective factor. In addition, evaluation of the predictive value revealed that acute chorioamnionitis, fetal distress, the placement of cervical ripening balloon catheter for >12h, and gravidity all had certain predictive value for the failure of cervical ripening double balloon combined with oxytocin for labor induction, with the highest predictive value found through joint predictive (AUC: 0.931, 95% CI: 0.714-0.811).

Conclusion: Cervical ripening double balloon combined with oxytocin for labor induction may have a high success rate in multigravida. Acute chorioamnionitis, fetal distress, and prolonged placement of the balloon may have a negative impact on the success rate of cervical ripening double balloon combined with oxytocin for labor induction.

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双球囊联合催产素引产：影响宫颈成熟效果的多变量因素分析

目的：妊娠晚期引产是通过药物或宫颈机械扩张诱发子宫收缩终止妊娠的常见选择。然而，有关宫颈成熟球囊联合催产素引产效果影响因素的研究却很少。目的：探讨影响宫颈成熟双球囊联合催产素引产效果的因素：本研究采用方便抽样的方法，回顾性收集了2021年9月至2022年8月在我院接受宫颈成熟双球囊联合催产素引产的230例孕妇的临床资料。根据分娩方式将纳入对象分为阴道分娩组（180 例）和剖宫产组（50 例），比较两组的相关指标：结果：急性绒毛膜羊膜炎（OR = 1.456，95% CI：1.257-2.112）、胎儿窘迫（OR = 1.371，95% CI：1.331-2.633）和宫颈成熟球囊导管放置时间超过 12 小时（OR = 1.563，95% CI：1.231-3.263）是成功应用宫颈成熟球囊导管的风险因素。263）是孕妇成功应用宫颈成熟双球囊联合催产素引产的危险因素；而多胎妊娠（OR = 0.736，95% CI：0.455-0.875）是保护因素。此外，预测值评估显示，急性绒毛膜羊膜炎、胎儿窘迫、宫颈成熟球囊导管放置时间大于 12 小时、葡萄胎均对宫颈成熟双球囊联合催产素引产失败有一定的预测价值，其中联合预测值最高（AUC：0.931，95% CI：0.714-0.811）：结论：宫颈成熟双球囊联合催产素用于多胎妊娠引产的成功率较高。急性绒毛膜羊膜炎、胎儿窘迫和球囊放置时间过长可能会对宫颈成熟双球囊联合催产素引产的成功率产生负面影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Women's Health OBSTETRICS & GYNECOLOGY-

CiteScore

3.70

自引率

0.00%

发文量

194

审稿时长

16 weeks

期刊介绍： International Journal of Women''s Health is an international, peer-reviewed, open access, online journal. Publishing original research, reports, editorials, reviews and commentaries on all aspects of women''s healthcare including gynecology, obstetrics, and breast cancer. Subject areas include: Chronic conditions including cancers of various organs specific and not specific to women Migraine, headaches, arthritis, osteoporosis Endocrine and autoimmune syndromes - asthma, multiple sclerosis, lupus, diabetes Sexual and reproductive health including fertility patterns and emerging technologies to address infertility Infectious disease with chronic sequelae including HIV/AIDS, HPV, PID, and other STDs Psychological and psychosocial conditions - depression across the life span, substance abuse, domestic violence Health maintenance among aging females - factors affecting the quality of life including physical, social and mental issues Avenues for health promotion and disease prevention across the life span Male vs female incidence comparisons for conditions that affect both genders.