Emerging and extensive clonal evolution in the pancreas.

IF 14.3 1区医学 Q1 ONCOLOGY

Trends in cancer Pub Date : 2024-08-01 Epub Date: 2024-07-07 DOI:10.1016/j.trecan.2024.06.011

Alvin P Makohon-Moore

引用次数: 0

Abstract

Pancreatic cancer is one of the most lethal malignancies, yet much remains to be learned regarding how its precursors develop. In a recent Nature publication, Braxton and Kiemen et al. found that the normal, adult pancreas harbors hundreds to thousands of pancreatic cancer precursors evolving by a variety of routes.

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胰腺新出现的广泛克隆进化。

胰腺癌是最致命的恶性肿瘤之一，但关于它的前体是如何发育的，还有很多知识有待了解。在最近发表的《自然》杂志上，Braxton 和 Kiemen 等人发现，正常的成人胰腺中蕴藏着成百上千的胰腺癌前体，它们通过各种途径进化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trends in cancer Medicine-Oncology

CiteScore

28.50

自引率

0.50%

发文量

138

期刊介绍： Trends in Cancer, a part of the Trends review journals, delivers concise and engaging expert commentary on key research topics and cutting-edge advances in cancer discovery and medicine. Trends in Cancer serves as a unique platform for multidisciplinary information, fostering discussion and education for scientists, clinicians, policy makers, and patients & advocates.Covering various aspects, it presents opportunities, challenges, and impacts of basic, translational, and clinical findings, industry R&D, technology, innovation, ethics, and cancer policy and funding in an authoritative yet reader-friendly format.