Childhood motor difficulties and cognitive impairment in midlife: A 40-year cohort study.

IF 2.6 3区心理学 Q3 NEUROSCIENCES

Neuropsychology Pub Date : 2024-09-01 Epub Date: 2024-07-08 DOI:10.1037/neu0000961

Ilkka Järvinen, Nella Schiavone, Jyrki Launes, Jari Lipsanen, Maarit Virta, Ritva Vanninen, Eliisa Lehto, Annamari Tuulio-Henriksson, Laura Hokkanen

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引用次数: 0

Abstract

Objective: We aimed to examine the association of childhood motor difficulties (MD) with cognitive impairment in midlife.

Method: We studied 357 participants from a cohort born in 1971-1975. At age 9, they had completed the Test of Motor Impairment, which classified them into three groups: childhood MD (cMD), borderline cMD (bcMD), or no cMD. Participants with attention-deficit/hyperactivity disorder were excluded. At age 40, participants comprised 18 (5.0%) with cMD, 43 (12.0%) with bcMD, and 296 (82.9%) with no cMD. They underwent neuropsychological assessment covering six domains: executive functions, processing speed, attention and working memory, learning and memory, verbal symbolic abilities, and visuoperceptual and visuospatial abilities. A participant was considered to have an impairment if their performance was in the 15th percentile of a normative group.

Results: Participants with cMD were more likely than those with no cMD to have an impairment in executive functions (OR = 6.73, p < .01), processing speed (OR = 3.85, p < .05), attention and working memory (OR = 4.79, p < .01), and a cross-domain impairment (OR = 3.62, p < .01). These differences remained significant after adjusting for parents' occupation, sex, and low birth weight and after multiple imputation. No consistent difference emerged between participants with bcMD and no cMD.

Conclusions: Childhood MD are associated with midlife cognitive impairment, which underscores their long-term implications. In the neuropsychological assessment of an adult patient, information on childhood motor development is of value. The assessment may help adapt the patient's physical or occupational therapy to the patient's cognitive profile. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

查看原文本刊更多论文

儿童时期的运动障碍与中年后的认知障碍：一项为期 40 年的队列研究。

目的我们旨在研究童年运动障碍（MD）与中年认知障碍之间的关系：我们对 1971-1975 年出生的 357 名参与者进行了研究。他们在 9 岁时完成了运动障碍测试，该测试将他们分为三组：儿童期运动障碍（cMD）、边缘型运动障碍（bcMD）或无运动障碍。患有注意力缺陷/多动障碍的参与者被排除在外。在 40 岁时，参与者中有 18 人（5.0%）患有 cMD，43 人（12.0%）患有 bcMD，296 人（82.9%）未患有 cMD。他们接受了涵盖六个领域的神经心理学评估：执行功能、处理速度、注意力和工作记忆、学习和记忆、语言符号能力以及视觉感知和视觉空间能力。如果受试者的表现位于常模组的第 15 百分位，则被视为存在障碍：与未患有 cMD 的人相比，患有 cMD 的人更有可能在执行功能（OR = 6.73，p < .01）、处理速度（OR = 3.85，p < .05）、注意力和工作记忆（OR = 4.79，p < .01）以及跨领域障碍（OR = 3.62，p < .01）方面存在障碍。在对父母的职业、性别和出生体重过轻进行调整并进行多重归因后，这些差异仍然显著。有 bcMD 和没有 cMD 的参与者之间没有出现一致的差异：结论：儿童期多发性硬化症与中年期认知障碍有关，这凸显了其长期影响。在对成年患者进行神经心理评估时，有关儿童期运动发育的信息很有价值。该评估有助于根据患者的认知状况调整其物理或职业疗法。(PsycInfo Database Record (c) 2024 APA, 版权所有）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neuropsychology 医学-神经科学

CiteScore

4.10

自引率

4.20%

发文量

132

审稿时长

6-12 weeks

期刊介绍： Neuropsychology publishes original, empirical research; systematic reviews and meta-analyses; and theoretical articles on the relation between brain and human cognitive, emotional, and behavioral function.