Impact of audiovestibular factors on prognosis in patients with sudden sensorineural hearing loss without vertigo.

IF 1.9 3区医学 Q2 OTORHINOLARYNGOLOGY

European Archives of Oto-Rhino-Laryngology Pub Date : 2024-11-01 Epub Date: 2024-07-08 DOI:10.1007/s00405-024-08789-5

Sheng-Chiao Lin, Ming-Yee Lin

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Abstract

Purpose: This study aimed to investigate the hearing outcomes in patients with sudden sensorineural hearing loss without vertigo (SSNHLwoV).

Methods: Patients with SSNHLwoV managed from December 2016 to March 2020 were prospectively enrolled in an academic tertiary referral center. Fifty-one patients with SSNHLwoV who completed high-dose steroid treatment. The hearing prognosis was analyzed using a multivariate Cox regression model.

Results: The rates of complete, partial, and no hearing recovery were 52.9%, 17.6%, and 29.4% in patients with SSNHLwoV, respectively. The video head impulse test (vHIT) of the posterior semicircular canal (PSC), high-tone hearing loss (4-8 kHz) ≥ 30 dB, and average hearing threshold (0.5-1-2-4 kHz) were significantly associated with incomplete recovery of hearing after treatment. In multivariate analysis, the vHIT of the PSC (hazard ratio [HR], 14.502; 95% confidence interval [CI], 1.371-153.355) and high-tone hearing loss ≥ 30 dB (HR, 9.170; 95% CI, 2.283-36.830) remained robust.

Conclusions: Abnormal vestibular function tests were performed in 80.4% of the patients with SSNHLwoV. Abnormal vHIT of the PSC and high-tone hearing loss ≥ 30 dB were independent factors resulting in incomplete recovery of hearing in patients with SSNHLwoV. In the SSNHLwoV cohort, the caloric test was not significantly associated with hearing prognosis, and vHIT was a feasible predictor of treatment outcome.

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听觉前庭因素对突发性感音神经性听力损失（无眩晕）患者预后的影响。

目的：本研究旨在调查无眩晕的突发性感音神经性听力损失（SSNHLwoV）患者的听力结果：在一家学术性三级转诊中心，前瞻性地纳入了 2016 年 12 月至 2020 年 3 月期间接受治疗的 SSNHLwoV 患者。51名SSNHLwoV患者完成了大剂量类固醇治疗。采用多变量考克斯回归模型分析了听力预后：结果：在 SSNHLwoV 患者中，听力完全恢复率、部分恢复率和未恢复率分别为 52.9%、17.6% 和 29.4%。后半规管视频头脉冲测试（vHIT）、高音听力损失（4-8 kHz）≥ 30 dB和平均听阈（0.5-1-2-4 kHz）与治疗后听力未完全恢复显著相关。在多变量分析中，PSC的vHIT（危险比[HR]，14.502；95%置信区间[CI]，1.371-153.355）和高音听力损失≥30 dB（HR，9.170；95% CI，2.283-36.830）仍然稳健：80.4%的 SSNHLwoV 患者前庭功能测试异常。PSC前庭功能测试异常和高音听力损失≥30 dB是导致SSNHLwoV患者听力未完全恢复的独立因素。在SSNHLwoV队列中，热量测试与听力预后无明显关联，而vHIT是预测治疗结果的可行指标。

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来源期刊

European Archives of Oto-Rhino-Laryngology 医学-耳鼻喉科学

CiteScore

5.30

自引率

7.70%

发文量

537

审稿时长

2-4 weeks

期刊介绍： Official Journal of European Union of Medical Specialists – ORL Section and Board Official Journal of Confederation of European Oto-Rhino-Laryngology Head and Neck Surgery "European Archives of Oto-Rhino-Laryngology" publishes original clinical reports and clinically relevant experimental studies, as well as short communications presenting new results of special interest. With peer review by a respected international editorial board and prompt English-language publication, the journal provides rapid dissemination of information by authors from around the world. This particular feature makes it the journal of choice for readers who want to be informed about the continuing state of the art concerning basic sciences and the diagnosis and management of diseases of the head and neck on an international level. European Archives of Oto-Rhino-Laryngology was founded in 1864 as "Archiv für Ohrenheilkunde" by A. von Tröltsch, A. Politzer and H. Schwartze.